Pathfinder Medical, which has developed a proprietary technology to guide and accurately align catheters in endovascular procedures allowing clinicians to make connections across blood vessels in the body without the need for open surgery, has announced securing £8.5 million. The...
Cancer, infections and heart disease pose the greatest risk to kidney transplant recipients—not organ rejection—according to a recently published Mayo Clinic study. Researchers discovered that recipient death due to factors other than organ rejection is the leading cause for...
Anais Medical, a new company founded by Parc Taulí Research and Innovation Institute (I3PT) and led by José Ibeas (nephrologist at Parc Taulí University Hospital, Barcelona, Spain), aims to develop practical educational material, which uses realistic models and simulations,...
There are some very serious risks associated with forgotten ureteric JJ stents. David Maudgil a consultant interventional radiologist at Wexham Park Hospital, Frimley Health Foundation Trust (Slough, UK), outlines why and when these devices are used, explains the risks...
Attempts to optimise the current state of play in vascular access for dialysis patients—from deployment of drug-coated balloons (DCBs) to more novel vein dilation technologies—piqued the interest of Renal Interventions readers throughout 2021. An in-depth interview with pioneering vascular...
Home haemodialysis provider Dialyze Direct has announced the acquisition of Renew Dialysis, a regional provider of on-site dialysis services in skilled nursing facilities (SNFs), with eight locations in Ohio and one in Virginia, that was co-founded by Saber Healthcare...
The Getting It Right First Time (GIRFT) national report on renal medicine represents a “call to action” for the UK renal community, and provides greater focus in driving quality improvement across care pathways for kidney disease. These were among...
Kidney transplant recipients tend to mount impaired antibody responses against emerging SARS-CoV-2 variants after standard two-dose COVID-19 vaccination, according to a study published in the Clinical Journal of the American Society of Nephrology (CJASN). The research shows this is also...
Hansa Biopharma recently announced that the first patient has been enrolled in its CONFIDES trial—a US pivotal, open-label, randomised controlled study—at the Columbia University Medical Center (New York, USA). The CONFIDES trial is evaluating the drug imlifidase as a potential desensitisation...
Fresenius Medical Care has announced the launch of Carrie, a custom-built mobile application intended to connect, inform and support Fresenius Kidney Care nurses and clinical teams in the Asia Pacific (APAC) region. Named ‘Carrie’ in recognition of the “limitless...
Zynex Monitoring Solutions recently reported it has started enrolment in a haemodialysis clinical trial with its CM-1500 fluid monitoring system. The study, conducted at DaVita Clinical Research clinics, is aimed at further characterising changes in the device's patented Relative...
Researchers from the University of Alabama at Birmingham (UAB; Birmingham, USA) and US firm Endomimetics are working to develop a long-sought-after, effective therapy that will promote healthy maturation in arteriovenous fistulas (AVFs)—and recently reported preclinical progress on this front...
A single-centre, retrospective, comparative study, which was presented at the July 2021 Journal of Vascular Surgery (JVS) Journal Club (14 July, online), has found that percutaneous arteriovenous fistula (pAVF) creation may be associated with lower rates of complication relating...
Fist Assist Devices has announced that it recently received Breakthrough Device designation from the US Food and Drug Administration (FDA) for its Fist Assist Model FA-1 device. According to the company, the FA-1 is the world’s first wearable device for...
Arteriovenous fistulas (AVFs) are widely considered to be the holy grail in dialysis access, providing a more long-term solution than synthetic arteriovenous grafts (AVGs) or central venous catheters (CVCs), with a reduced risk of complications. However, these benefits only...
DaVita has recently become the first kidney care provider to completely power its North American operations with renewable energy, according to a press release from the company. DaVita achieved this goal, which it set in 2019, by contracting with Longroad...
Video-based telemedicine is used to facilitate care across all stages of chronic kidney disease (CKD) and has evolved in recent years to be less reliant on specialised equipment, allowing patients to receive kidney care in a location of their...
 Nicholas Inston (consultant vascular access and renal transplant surgeon, Birmingham, UK) discusses the crucial care interventional radiologists provide for renal patients with Ian Mcafferty (consultant interventional radiologist, Birmingham, UK, and immediate past president of the British Society of Interventional...
 Nicholas Inston (Birmingham, UK) talks to CX about the challenges in creation, maintenance and salvage of vascular access in patients with end stage renal disease. Inston highlights the many innovations and technologies that have come to the forefront in recent...
 Alexandros Mallios (Paris, France) and Robert Shahverdyan (Hamburg, Germany) talk to Vascular News about some of the benefits of the Ellipsys™ Vascular Access System (Medtronic), how it compares to more traditional fistula creation techniques, and the key steps for...
Cleaning and low-level disinfection (LLD) effective against bloodborne pathogens are safe and sufficient procedures for disinfecting ultrasound transducers used in percutaneous procedures—this is according to an intersocietal position statement recently issued by the American Institute of Ultrasound in Medicine...
NYU Langone Health has performed a second successful investigational xenotransplantation procedure using a genetically engineered pig kidney. This second surgery is a sign of continued progress toward a potential alternative supply of life-saving organs. Leading the second surgical procedure was...
Huge strides have been made in preventing contrast-associated acute kidney injury among patients undergoing percutaneous coronary intervention (PCI) and other interventional procedures in recent decades, Roxana Mehran (Icahn School of Medicine at Mount Sinai, New York, USA) tells Cardiovascular...
SyMap Medical has announced the completion of a financing round that will be used to accelerate global clinical trials for the company’s renal mapping and selective renal denervation systems. The financing round of nearly US$100 million was led by Primavera...
Alio has announced a partnership with Lifeline Vascular Care in support of patients living with end-stage renal disease (ESRD). Alio leverages artificial intelligence (AI) and the company’s SmartPatch sensor technology to non-invasively monitor vascular access health and other chronic...
 The Amplifi Vein Dilation System (Artio Medical) is an innovative device designed to dilate arm veins in preparation for arteriovenous fistula (AVF) surgery using rapid, non-pulsatile venous blood flow. Surendra Shenoy, M.D. (a vascular surgeon with specialist interest in...
Artio Medical has announced that full results from its first-in-human clinical study of the Amplifi vein dilation system were presented at the 2021 VEITHSymposium (16–20 November, Orlando, USA and virtual) by Surendra Shenoy, associate professor of surgery in the Washington University School...
An observational study published in the Journal of the American Society of Nephrology (JASN) has identified a “promising” histological marker for determining kidney transplant failure. A collaboration between Kyoto University and Akita University in Japan—led by Motoko Yanagita, a professor...
University of Maryland Medicine—which is comprised of the University of Maryland Medical System (UMMS) and the University of Maryland School of Medicine (UMSOM)—has announced that it will end the use of a long-standing clinical standard for measuring kidney function...
Dialysis patients who received mRNA COVID-19 vaccines had a lower risk of COVID-19 diagnosis post-vaccination, and were less likely to be hospitalised or die following breakthrough infection compared to unvaccinated patients. That is according to a study announced today...
RenalSense recently announced it has secured US$14 million to bolster the global commercialisation of its current product, the Clarity RMS, expand clinical validation to additional clinical settings, and advance the release of its next-generation products based on its sensor platform. The...
An updated risk score to predict possible contrast-associated acute kidney injury (CA-AKI) among patients undergoing percutaneous coronary intervention (PCI) has been presented by Roxana Mehran (Icahn School of Medicine at Mount Sinai, New York, USA) at the American Heart...
New technologies intended to improve the often-mixed outcomes associated with arteriovenous grafts (AVGs) for haemodialysis access were on display at this year’s Vascular Access Society of Britain & Ireland scientific meeting (VASBI; 16–17 September 2021, virtual). In addition to...
There are several different types of dialysis treatment available to kidney disease patients—with the three major players, in-centre haemodialysis (ICHD), home haemodialysis (HHD) and peritoneal dialysis (PD) all holding their own benefits and drawbacks. Mark Lambie, a senior reader...
Simulations Plus has announced that its DILIsym Services division has released RENAsym version 1A, the first version of its novel quantitative systems toxicology (QST) software for predicting and investigating drug-induced kidney injury. RENAsym modelling supports key drug development decisions by predicting potential...
Baxter Asia Pacific (Baxter) has announced the launch of My Kidney Journey—a comprehensive online portal intended to support patients living with chronic kidney disease (CKD) in the Asia Pacific (APAC) region. CKD is becoming more prevalent in countries across Asia and continues to be a...
Fresenius Medical Care recently presented its advances in home dialysis solutions at the China International Import Expo (CIIE) in Shanghai, China. The company showcased new digitalised options that enable patients with end-stage renal disease (ESRD) to perform dialysis in...
Early data have indicated that a national project, dubbed MAGIC (Managing access by generating improvements in cannulation), has improved cannulation techniques of haemodialysis accesses in UK centres. Katie Fielding, a haemodialysis nurse and trainee advanced clinical practitioner (ACP) at...
People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from COVID-19—and new research has revealed that these individuals have profound immune system-related differences compared with people with...

Alexandros Mallios

Born and raised in the small lakeside city of Kastoria in northern Greece, Alexandros Mallios’ 15-year journey as a vascular surgeon has seen him complete a year of national service in the Greek military, travel to far-flung parts of...
The National Kidney Foundation (NKF) has announced the appointment of three new members to its national Board of Directors. The new members, Hubert L Allen (Chicago, USA), Renée Richardson Gosline (Cambridge, USA) and Alison Steiber (Shaker Heights, USA), were nominated and approved at...
OrganOx, the producer of the 'metra' normothermic machine perfusion (NMP) product, has announced the completion of a £6.4 million equity fundraise. The fundraise was led by Oxford Investment Consultants and supported by both existing and new shareholders. According to a...
 The upcoming Controversies in Dialysis Access (CiDA) meeting in Dallas, Texas is stepping up the scrutiny on the controversies and questions currently igniting the dialysis community, Bart Dolmatch (Portola Valley, USA) tells Renal Interventions at the Paris Vascular Insights...
New research presented at the American Society of Nephrology (ASN) Kidney Week (2–7 November 2021, virtual) indicates that substantial discrepancies exist between two major tools used to assess kidney function—estimated glomerular filtration rate (eGFR) and measured glomerular filtration rate...
The Ellipsys vascular access system (Avenu Medical/Medtronic) can be used to easily and safely create durable percutaneous arteriovenous fistulas (pAVFs) for haemodialysis—with new, long-term data suggesting it offers an “excellent alternative” to AVF creation via surgical procedures in end-stage...
The results of several high-impact clinical trials with the potential to impact kidney-related medical care in the future were presented at this year’s American Society of Nephrology (ASN) Kidney Week (2–7 November 2021, virtual). Highlights from this session included...
Randomised placebo-controlled trials show consistently that renal denervation provides significant reduction in ambulatory and office blood pressure, the findings of a systematic review and meta-analysis suggest. Findings of the paper, authored by Yousif Ahmad (Yale School of Medicine, Yale University,...
Six-month outcomes from the randomised RADIANCE-HTN TRIO trial, comparing endovascular ultrasound renal denervation to a sham procedure for treatment-resistant hypertension, demonstrate the additional effects of pharmacologic intervention with maintenance of a blood pressure-lowering effect of renal denervation at six...
Medtronic today announced findings from a new study of patient preferences for the treatment of hypertension. The findings are set to be presented during the “What's Novel in Interventional Hypertension” session at the 33rd Transcatheter Cardiovascular Therapeutics annual meeting (TCT...
At the 12th Congress of the Vascular Access Society (VAS; 6–9 April 2021, online), Ramon Roca-Tey, senior consultant in nephrology at the Fundación Sanitaria Mollet’s Hospital de Mollet in Barcelona, ​​Spain, and president of the Spanish Multidisciplinary Group for...
Natera has announced initial results from the global, multicentre, prospective Trifecta study, which assessed its Prospera with quantification test for kidney transplant rejection and was led by Phil Halloran, director, Alberta Transplant Applied Genomics Centre (Edmonton, Canada). "These new data from the Trifecta study...

Renal Interventions 1 – US

Renal Interventions debuts with a diverse range of hot topics and leading insight from the kidney care field, including: The introduction of a new, race-free approach to diagnosing kidney disease Highlights from the 2021 Vascular Access Society of Britain &...

Renal Interventions 1 – EU

Renal Interventions debuts with a diverse range of hot topics and leading insight from the kidney care field, including: The introduction of a new, race-free approach to diagnosing kidney disease Highlights from the 2021 Vascular Access Society of Britain...
Procyrion has announced the presentation of studies at the Transcatheter Cardiovascular Therapeutics annual meeting (TCT 2021, 4–6 November, Orlando USA and virtual) relating to its Aortix percutaneous mechanical circulatory support device. The presentations include a spotlight on the company's...
Outset Medical has announced that its Tablo haemodialysis system has received the first ever approval from the Centers for Medicare & Medicaid Services (CMS) for a Transitional Add-on Payment Adjustment for New and Innovative Equipment and Supplies (TPNIES). This pioneering...
In the future, a global approach to help standardise clinical practice guidelines for kidney disease may be the ideal way forward. This was the closing message from Charmaine Lok (University of Toronto, Toronto, Canada) following a session at the...
Twelve-month results from a first-in-human study of the Wrapsody cell-impermeable endoprosthesis (Merit Medical Systems) for the treatment of access circuit stenosis in haemodialysis patients are “very encouraging”. This is according to James Gilbert, a consultant transplant and vascular access...
The Centers for Medicare & Medicaid Services (CMS) is taking action to close health equity gaps by providing Medicare patients living with end-stage renal disease (ESRD) with greater access to care, according to a press release. Through the ESRD...
VenoStent has announced successful enrolment in its initial feasibility clinical trial. The clinical trial is testing the safety and efficacy of its 3D-printed bioabsorbable wraps in humans—a new methodology to improve surgical outcomes for haemodialysis patients. Enrolment was completed for...
The first investigational transplantation of a genetically engineered, non-human kidney to a human body was recently completed at NYU Langone Health, New York, USA—marking a major step forward in potentially utilising an alternative supply of organs for people facing...
Strive Health has announced Strive Care Partners (SCP)—a dedicated platform that enables nephrologists to share and succeed in global risk contracts with payors, according to a press release. Strive Care Partners will benefit patients with chronic kidney disease (CKD) and...
Quanta Dialysis Technologies announced today the results of the UK Dialysis Patient Experience Survey, showing the wide variance in care experienced by UK dialysis patients, as well as challenges faced in assessing self-care and home haemodialysis (HHD).  The survey revealed: ...
Despite the well-known obstacles, it is time for a prospective, randomised clinical trial comparing percutaneous ablation (PA) and partial nephrectomy for the treatment of small renal cell carcinomas—and re-thinking the common practice of watching and waiting, rather than intervening,...
There are multiple barriers to home dialysis initiation, and these disproportionately affect vulnerable populations. Current solutions need to be scaled up, with particular emphasis on educating physicians on home dialysis, improving modality education, increasing support for patients and families,...
Medtronic has announced receipt of a CE mark for its Hugo robotic-assisted surgery (RAS) system, authorising the sale of the system in Europe. This CE mark approval is for urologic and gynaecologic procedures, which make up about half of all robotic...
Despite an older dialysis population, the proportion and survival of arteriovenous fistulas (AVFs) in Danish dialysis patients has not changed over a 39-year period. This is the main conclusion of a national cohort study published online in The Journal...
Journey Biosciences—a biotechnology company with a proactive diagnostic screening technology for high-risk kidney complications associated with diabetes, has announced its company launch, and the introduction of its flagship product, NaviDKD. NaviDKD is a diagnostic screening technology that analyses blood-based predictive...
Several subgroups of patients treated with the IN.PACT AV drug-coated balloon (DCB; Medtronic) for arteriovenous fistulas (AVFs) demonstrated a “statistically significant” higher rate of target lesion primary patency (TLPP) compared to those who underwent standard percutaneous transluminal angioplasty (PTA)...
Preliminary clinical results from a first-in-human study assessing the Amplifi vein dilation system (Artio Medical) were presented at this year’s Vascular InterVentional Advances conference (VIVA; 4–7 October 2021, Las Vegas, USA). Data were presented by Surendra Shenoy—an associate professor of...
ReCor Medical has announced that its Paradise ultrasound renal denervation system is now available for the treatment of uncontrolled hypertension in Germany. The first hospitals performing the procedure commercially are Heart Center Leipzig, Leipzig and Saarland University Hospital, Homburg/Saar. “Despite...
Fresenius Medical Care North America (FMCNA) has announced three key clinical leadership appointments to help drive priorities, including improving patient outcomes, adopting connected health technologies to support home dialysis and increasing access to transplantation, according to a company press release. Kathleen...
NOTE: This advertorial is ONLY available to watch in selected countries and geographies This advertorial, sponsored by BD, is intended for readers in the EMEA region only. Rethink fistula creation and maintenance with Tobias Steinke, Ounali Jaffer, Panagiotis Kitrou and...
Merit Medical Systems has announced positive results from a prospective, observational, first-in-human study to evaluate the safety and effectiveness of Wrapsody—a self-expanding, cell-impermeable endoprosthesis designed for the treatment of arteriovenous (AV) fistula access circuit stenosis and AV graft access...
Bluegrass Vascular Technologies (Bluegrass Vascular) announced today that the Centers for Medicare & Medicaid Services (CMS) has finalised a new Healthcare Common Procedure Coding System (HCPCS) code and New Technology Ambulatory Payment Classification (APC) assignment for use of the...
Following the release of the European Society of Hypertension’s (ESH’s) updated position paper on renal denervation, Konstantinos Tsioufis, professor of Cardiology at the University of Athens, Athens, Greece and immediate past president of ESH, discusses the use of renal...
DaVita Kidney Care has marked Nephrology Nurses Week by announcing the appointment of Tina Livaudais as its chief nursing officer (CNO). Livaudais most recently served as vice president of clinical services for the National Hospital Services Group, overseeing more...
An implantable bioartificial kidney device (iBAK)—which promises to free kidney disease patients from dialysis machines and transplant waiting lists—has taken another step towards becoming a reality after being awarded a US$650,000 prize from KidneyX. The device’s creator, the Kidney...
Natera has announced the launch of Prospera with quantification, the only cell-free DNA (cfDNA) test for kidney rejection that provides three values—the quantity of donor-derived cfDNA (dd-cfDNA), fraction of dd-cfDNA, and total cfDNA—on every report. Combining these three metrics...
European Society of Hypertension (ESH), the leading hypertension (HTN) society in Europe, presented an updated position paper on renal denervation (RDN) during the eighth pre-ESH congress satellite symposium (10–11 September; Athens, Greece). The paper was recently published in the...
Black transplant recipients and patients who received kidneys from Asian donors had a significantly higher risk of their kidney grafts failing within seven years, according to a new study presented at the European Society for Organ Transplantation Congress (ESOT...
The number of solid organ transplants performed during the first wave of the COVID-19 pandemic in 2020 plunged by nearly a third (31%) compared to the previous year, according to a new global study presented at the European Society...
ImpediMed, an Australia-based medical technology company using bioimpedance spectroscopy (BIS) to generate powerful data to improve patient health, has announced that the Sozo digital health platform has been designated as a Breakthrough Device by the US Food and Drug...
Rubicon Founders has announced the launch of Evergreen Nephrology—a company partnering with nephrologists to transform kidney care, according to a press release. Evergreen is focused on transforming kidney care for patients across the USA and believes that nephrologists are...
Fresenius Medical Care North America (FMCNA) and Cigna have announced an expansion of their national effort to improve health outcomes and lower the cost of care for people living with kidney failure, or end-stage renal disease (ESRD). The new...
A patient-level meta-analysis of randomised controlled trials (RCTs) has shown that drug-coated balloons (DCBs) were “consistently favoured” over percutaneous transluminal angioplasty (PTA) to prolong target lesion primary patency and access circuit primary patency in the treatment of dysfunctional haemodialysis...
While the average time spent on a waitlist for a kidney transplant in South Carolina is 42 months, changes to the U.S. kidney allocation system could result in reduced access to kidney transplants and further time on waiting lists,...
Fist Assist Devices has announced that data associated with the p-FACT cohort, a subset of the recently completed, non-significant risk Fist Assist clinical trial (FACT trial) that focused on vein dilation in stage four patients with chronic renal failure,...
A pilot study has begun to assess the antibody response to a third dose of an authorised COVID-19 mRNA vaccine in kidney transplant recipients who did not respond to two doses of the Moderna or Pfizer-BioNTech COVID-19 vaccine. The...
The Society for Cardiovascular Angiography and Interventions (SCAI) has released a proceedings document outlining the possible role of renal denervation (RDN) as a therapeutic option to complement medical therapy and lifestyle interventions for patients with uncontrolled hypertension. The document...
Fist Assist Devices has just announced completion of the FACT trial, which evaluated the use of an intermittent pneumatic compression device, model FA-1, to promote vein dilation in patients with kidney disease. The trial’s results suggest the device could...
Through collaboration with Amazon Web Services (AWS), Baxter International is using cloud technology solutions to accelerate its company-wide digital transformation. According to a Baxter press release, this transformation will take place across three strategic areas—developing new digital health solutions...
Failure of home haemodialysis (HHD) treatment, defined as a return to in-centre haemodialysis (ICHD), has been associated with a “significant increase” in mortality when compared to continued HHD—a trend that was observed in both the early (first 30 days...
Artio Medical announced today it has completed enrolment in its first-in-human study evaluating the Amplifi vein dilation system. In the study, five patients were treated by Adrian Ebner, head of the Cardiovascular Department at Sanatorio Italiano Hospital in Asunción, Paraguay. "I am very...
The National Kidney Foundation (NKF) has released a position paper, developed by 16 nephrology experts from 13 institutions, with recommendations designed to navigate future research and innovation addressing the most pressing barriers to kidney transplant access, organ availability, and long-term...
A large, single-centre retrospective study has revealed the risk of acute kidney injury (AKI) following pharmacomechanical thrombolysis (PMT) for lower extremity deep vein thrombosis (DVT) is as high as 22%. PMT is an established treatment for selected patients with acute...
A retrospective analysis published in the Journal of Vascular Access (JVA) has shown that the oversized balloon angioplasty technique to assist arteriovenous (AV) fistula maturation is safe and effective—and allows cannulation of the fistula within hours or days of...
Polar Speed—UPS Healthcare's UK operation—has announced a five-year commercial agreement with Fresenius Medical Care to provide warehouse and transport solutions for the delivery of renal services and treatments to patients, and customers, in the UK. Through this agreement, Polar Speed...
A nationwide survey distributed among 150 randomly selected dialysis facilities in the USA has found that a “substantial proportion” of patients receiving in-centre haemodialysis are hesitant about seeking a COVID-19 vaccination. Notably, this proportion is still thought to be...
Results from a new study support the validity of a score that considers various patient-reported measures and preferences for assessing health-related quality of life, and promoting patient-centred care, in individuals with kidney failure. The study appears in the most...
Hansa Biopharma has announced three-year follow-up data on graft survival rates in crossmatch positive patients who received imlifidase prior to kidney transplantation. As reported in the article, which the company states has been accepted for publication in the American...
Multidisciplinary panel of UK experts agrees on roadmap and optimal stepwise application of interventions for symptomatic AVF stenoses in haemodialysis patients. Ounali Jaffer (London, UK) talks to Renal Interventions about the team's recent publication in CVIR.
Diaverum, a global renal care service provider, has launched its first ever holiday dialysis travel guide in an effort to “empower renal patients worldwide to live out their dreams of travel, whilst maintaining access to the vital, life-saving treatments...
 Nicholas Inston (Queen Elizabeth Hospital Birmingham, Birmingham, UK), secretary of the Vascular Access Society (VAS) and chairman of the editorial board for Renal Interventions interviews Christoph Wanner (University Hospital Würzburg, Würzburg, Germany), president of the European Renal Association (ERA). They talk...
With national guideline writers in the UK and other countries weighing up the role of the Kidney Failure Risk Equation (KFRE) from a renal referrer’s perspective, including in primary care, new research finds that both the four- and eight-variable...
This year's American Association of Kidney Patients (AAKP) policy summit highlighted the challenges and opportunities for researchers and companies involved in safely bringing new, or expanding, kidney care innovations to consumer markets. The consistent messages shared among all 2021...
Alio Medical, a wearable technology company enabling insights through clinical grade real-time data, has announced the close of a financing round totalling US$20 million. The company says it will use the funding to conduct clinical studies on expanded indications and...
DaVita Kidney Care has announced the expansion of its home kidney care programme to include the HomeChoice Claria Automated Peritoneal Dialysis (APD) system, enabled by Sharesource remote patient monitoring from Baxter International. For many patients with kidney failure, choosing a...
DaVita Kidney Care has launched virtual support groups through DaVita Care Connect, a mobile health platform designed for home dialysis patients, which the company says aims to help create a community for those undergoing treatment at home. "Patients treating at...
Kidney Care Partners (KCP)—a US multi-stakeholder coalition representing patient advocates, physician organisations, health professional groups, dialysis providers, researchers and manufacturers—has relaunched the Kidney Care Quality Alliance (KCQA) in an effort to develop meaningful measures to evaluate facility-level quality performance,...
Quanta Dialysis Technologies has announced that it has raised US$245 million in an oversubscribed and upsized Series D financing round—the largest private funding round for a dialysis device company in history, according to a press release from the firm—which...
The largest randomised controlled trial comparing long-term surgical outcomes between two different anaesthetic techniques, the ACCESs study, has just launched in the UK, to test whether regional, when compared to local, anaesthesia during arteriovenous fistula (AVF) creation will confer...
Despite the device demonstrating no serious adverse events (SAEs) in a preliminary safety study, researchers believe further enhancements are needed to improve the outcomes associated with the automated wearable artificial kidney (AWAK)-PD system (AWAK Technologies) for peritoneal dialysis patients....
Fist Assist Devices has received US Food and Drug Administration (FDA) 510(k) clearance for use of the Fist Assist FA-1 device in the USA as an arm massage and increased vein circulation device, and has commenced marketing the Fist...
Medtronic has announced the first patient procedure with the Hugo robotic-assisted surgery (RAS) system. The robotic prostatectomy was performed by urological surgeon Ruben Olivares (Clínica Santa Maria, Santiago, Chile) and, according to a company press release, marks the beginning of the Hugo...
Concept Medical has provided an update on the progress of the IMPRESSION (sirolimus-coated balloon angioplasty versus plain balloon angioplasty in the treatment of dialysis access dysfunction) trial—a prospective, multicentre, two-arm parallel group, randomised clinical study designed to assess the efficacy of...
New research indicates that patients with kidney failure who receive care at for-profit dialysis facilities are less likely to be referred for kidney transplants than those receiving care at non-profit facilities. These findings appear in the Clinical Journal of...
Dialysis provider US Renal Care recently announced it has finished administering a second round of mRNA vaccines to ensure better protection against COVID-19 for thousands of vulnerable patients on dialysis. "The administration of vaccines to our patients and their caregivers...
Monogram Health, a benefit management and care delivery company attempting to transform care for individuals with chronic kidney disease (CKD) and end-stage renal disease (ESRD), has announced the closing of a Series B funding round worth US$160 million. The...
A new study, published online in The Journal of Vascular Access (JVA), suggests that arteriovenous fistulas (AVFs) contribute to higher survival of haemodialysis patients with COVID-19. Authors Ahmet Murt (Istanbul University-Cerrahpasa, Istanbul, Turkey) and colleagues urge that end-stage renal...
When it comes to treating steal syndrome, the extent to which the dialysis patient in question is displaying symptoms—as well as their flow rate and the location of their anastomosis—should all be taken into consideration. This concept was presented...
Baxter International, a global innovator in renal care, has announced new data showing expanded haemodialysis (HDx) therapy enabled by the company's Theranova dialyser may reduce cardiovascular events by 35% and hospitalisation rates by 18%. This data comes from a...
Tackling the main culprit, stenosis in the arteriovenous anastomosis and outflow veins, with balloon angioplasty before it is “too late” can boost maturation rates in slow-to-mature arteriovenous (AV) fistulas. Robert Jones, consultant interventional radiologist at the Queen Elizabeth Hospital...
Fresh evidence on the usefulness of sonography to ease the burden of lung congestion in haemodialysis patients and “promising data” on a long-awaited targeted treatment for immunoglobin A nephropathy (IgAN) were among the highlights of several late-breaking presentations at...
Fresenius Medical Care has made its own dialysis clinics available for the vaccination of its patients against COVID-19. Dialysis patients are an especially high-risk group due to the fact they are on average, over the age of 65, and often...
Acute kidney injury (AKI) treated with dialysis is reported to be a frequent complication in patients hospitalised with COVID-19. Research published online in the Clinical Journal of the American Society of Nephrology in late May reveals that machine learning...
Many individuals with kidney failure have been unable to self-isolate during the COVID-19 pandemic because they require dialysis treatments in clinics several times a week. New research that will appear in an upcoming issue of the Clinical Journal of...
Researchers from the Lawson Health Research Institute at London Health Sciences Centre (LHSC) in London, Canada have reported that a simple medical device reduced swelling after kidney transplantation, as well as shortening hospital stays and decreasing surgical site infections,...
 Andrew Holden (Auckland, New Zealand) presents the latest results from the IN.PACT™ AV Access trial (Medtronic), which indicate “outstanding” target-lesion primary patency rates of 52.2% through 24 months in dialysis patients with dysfunctional arteriovenous fistulas (AVFs), offering a “highly-significant advantage” over standard...
Following a successful proof-of-concept study, Gerard S Goh and Markus P Schlaich have embarked upon a first-in-human study to explore the safety and efficacy of combined renal and common hepatic artery denervation in patients with type 2 diabetes and...
The field of vascular access care for haemodialysis patients may look very different in just a few years’ time, with a host of new, innovative technologies currently being developed and tested to help tackle existing challenges relating to infection,...
Those living with kidney disease need better, more relevant patient education to best participate in the decision-making about their treatment, a new study published in the National Kidney Foundation (NKF)’s American Journal of Kidney Diseases (AJKD) shows. In a report...
In addition to demonstrating comparable performance in terms of long-term patency, durability and associated complications, early-cannulation arteriovenous (AV) grafts may hold some advantages when contrasted with standard expanded polytetrafluoroethylene (ePTFE) graft products. That is according to transplant and vascular...
The European Union (EU) Medical Devices Regulation (MDR) takes effect from today (26 May 2021). The Regulation revises quality and safety standards and the range of regulated devices and was first initiated in May 2017, with an initial three-year transition...
Procyrion has announced the treatment of the first patients in a pilot trial to evaluate the performance of its novel Aortix percutaneous mechanical circulatory support (pMCS) device in patients with cardiorenal syndrome (CRS). The company began its trial in...
 Ajay Kirtane (New York, USA) talks to Renal Interventions about the RADIANCE-HTN TRIO trial which compared renal denervation with a sham procedure to see whether or not renal denervation could lower blood pressure out to two months in patients...
Additional randomised controlled data regarding the effectiveness of drug-coated balloons (DCBs) in maintaining arteriovenous (AV) access offers new evidence, but it is freighted with uncertainty. However, specific modelling suggests fewer reinterventions could reinforce economic benefits when the IN.PACT AV...
Ultrasound-based endovascular renal denervation can successfully reduce systolic blood pressure in patients with medication-resistant hypertension, as demonstrated by the results of a late-breaking clinical trial presented at the American College of Cardiology’s 70th Annual Scientific Session (ACC.21, 15–17 May,...
Through its Renal Therapies Group, Fresenius Medical Care North America (FMCNA) has introduced the Kinexus Therapy Management Platform—a new connected health platform for home dialysis that supports the management of a patient's peritoneal dialysis therapy on the company’s Liberty...
Medtronic today announced new clinical data from the Global SYMPLICITY registry (GSR) indicating that renal denervation with the Medtronic Symplicity renal denervation system was associated with clinically significant and sustained blood pressure reductions in a real-world hypertensive patient population...
American healthcare firm and global renal care innovator Baxter International has announced US Food and Drug Administration (FDA) 510(k) clearance of its next-generation Artificial Kidney 98 (AK 98) dialysis machine, which is designed to be a portable and easy-to-use...
In a recent study, Victor Demaerel (University Hospitals Leuven, Leuven, Belgium) and colleagues found that tunnelled haemodialysis catheter (THC) survival in 352 patients was more than 70% after five years. This finding, they conclude, “supports use for permanent...
Despite currently being less commonly used than metal needles in haemodialysis access, particularly in Europe, plastic cannulas offer a “useful new tool in the box” for renal nurses, thanks to their ability to lessen blood extravasation and reduce the...
In its current form, postprocedural surveillance of arteriovenous grafts (AVGs) used to treat venous stenosis is “little more than supervised neglect”, and should be re-evaluated using the right patient cohorts and treatment strategies. That is according to a discussion...
Transit Scientific has announced CE mark clearance for its XO Score scoring sheath platform, allowing the technology to be used in the treatment of peripheral arterial disease (PAD) and end-stage renal disease (ESRD) within the European Union. XO Score is...
Discussions at this year’s Charing Cross (CX) 2021 Digital Edition (19–22 April, online) indicated that high-flow arteriovenous (AV) fistulas remain one of the more divisive topics in the field of vascular access. This was most apparent in the outcome...
Invizius has announced the closing of a Series A financing round worth £5.3 million. The Scottish biotechnology company will use this funding to complete a first-in-man safety study next year of its H-Guard Priming Solution, which is intended to...
Metavention, a Minneapolis-headquartered medical device company, has announced the initiation of the MODUS study to treat patients with both type 2 diabetes and hypertension using a minimally-invasive, catheter-based approach. The first procedures in this study were successfully completed at The...
A new wearable device designed to remotely monitor arteriovenous (AV) fistulae function in dialysis access patients uncovered promising data leading one set of researchers to conclude the technology offers hope for improved care and lower costs among a challenging...
iVascular has received CE mark approval for its balloon-expandable covered stent, iCover, a press release from the company states. Balloon-expandable covered stents are commonly used for treating arteriosclerotic lesions in renal and iliac arteries, and for the treatment of aneurysms...
Vascular Therapies recently announced results from its phase 3 clinical trial in which Sirogen showed encouraging arteriovenous fistula (AVF) outcomes in elderly end-stage renal disease (ESRD) patients. Sirogen is the company's proprietary sirolimus formulation for intraoperative local drug delivery to...
BD announced today that enrolment has begun and the first patients have been treated in the postmarket surveillance study, CONNECT-AV. CONNECT-AV is a prospective, single-arm, open-label study that will follow patients treated with the WavelinQ endovascular arteriovenous fistula (endoAVF) system...
A small, randomised trial conducted in a UK dialysis unit has found that ultrasound guidance can improve cannulation accuracy—and this improvement may be most profound in arteriovenous (AV) fistulas that are more difficult to cannulate. These findings, which were presented...
Medtronic recently announced the safety and effectiveness results through 24 months for the IN.PACT AV Access clinical study. The data, which were presented virtually as a Podium 1st at the Charing Cross (CX) 2021 Digital Edition (19–22 April, online)...
Massachusetts-based physician organisation InterWell Health has announced the closing of a Series B funding round worth US$46 million. The company claims this funding round will bring together more than 1,000 nephrologist investors representing 55 different nephrology practices and 31...
Consensus is split over the need for flow reduction in high-flow fistulas to avoid cardiac complications in dialysis patients, polling taken during the Charing Cross (CX) 2021 Digital Edition (19–22 April, online) has revealed. Attendees to the Vascular Access...
Clotted haemodialysis accesses can spontaneously recanalise following a failed thrombectomy and subsequent abandonment, a retrospective review of 3,137 mechanical thrombectomy procedures has found. The study was presented at the 2021 meeting of the Society of Interventional Radiology (SIR; 20–26...
American medical technology company BD (Becton, Dickinson and Company) has received 510(k) clearance from the US Food and Drug Administration (FDA) for its Pristine long-term haemodialysis catheter—a new haemodialysis catheter with a unique side hole-free symmetric Y-tip distal lumen...
A multicentre clinical trial to assess arteriovenous fistula (AVF)-first and arteriovenous graft (AVG)-first access strategies in older end-stage renal disease (ESRD) patients on haemodialysis has been deemed feasible following a two-year pilot study investigating the same topic. The findings of...
Shanghai-based renal denervation (RDN) company Brattea has announced the successful completion of a Series B+ funding round worth more than US$20 million led by healthcare private equity fund Kuanping Capital.  According to a press release from Brattea, this is the...
Cricket Health has announced a new kidney care programme specifically designed for late-stage chronic kidney disease (CKD) and end-stage renal disease (ESRD) patients enrolled in Medicare Advantage (MA) plans. The US company claims its programme—which has been launched to more...
Surmodics recently announced the successful first uses with patients for two devices within its Sublime radial access platform: the Sublime radial access guide sheath and Sublime radial access .014 RX percutaneous transluminal angioplasty (PTA) dilatation catheter. Constantino Pena, Andrew Niekamp,...
While there is large variability based on the site of insertion, patient characteristics and previous accesses, fluoroscopically-guided insertion of tunnelled central venous catheters (td-CVC) for dialysis can be considered a “low exposure” procedure, according to a report. The report, which...
“International practice differences exist in cannulation and dialysis provision with some approaches aiming for fistulas to suit the logistics of dialysis, rather than best long-term outcomes for the fistula and the patient” The CX 2021 Vascular Access Controversies Programme is designed to...
Fresenius Medical Care North America and DaVita Kidney Care have announced an expanded agreement to make multiple home dialysis technologies available for patients across the USA. Following this new agreement between the two American companies—which intends to encourage more people...
MedAlliance has announced completion of patient enrolment in the ISABELLA clinical trial with the Selution SLR 018 drug-eluting balloon (DEB) for the treatment of dysfunctional arteriovenous (AV) fistulas in end-stage renal failure patients undergoing haemodialysis. Selution SLR (sustained limus...
NOTE: This video is ONLY available to watch in selected countries and geographies Robert Lookstein (New York, USA; principal investigator) and Andrew Holden (Auckland, New Zealand; principal investigator) discuss the key six-month results and implications from the IN.PACT™ AV...
 A trio of vascular experts including Raphaël Coscas (Paris, France), Alexandros Mallios (Paris, France) and Kate Steiner (Stevenage, UK) discuss the key findings of the IN.PACT™ AV Access trial–which was recently published in the New England Journal of Medicine...
New data presented for the first time at LINC 2021 (The Leipzig Interventional Course; 25–29 January, online) support the use of drug-coated balloons (DCBs) as a treatment for dysfunctional arteriovenous fistulas (AVFs). The audience also heard the case for...
Humacyte has announced that the clinical results of five-year outcomes in patients receiving the human acellular vessels (HAV) for arteriovenous (AV) access in haemodialysis have been accepted for oral presentation at the Charing Cross (CX) Symposium (19–22 April, online)....
A tunneled catheter remains the most common access in patients initiating haemodialysis.1 This is most likely because the catheters are ready to use immediately after insertion, with no maturation time needed. As with any other dialysis access, hydraulic performance...
Panagiotis M Kitrou and Nicholas Inston discuss the impact of the COVID-19 pandemic on vascular access services. Despite the disruption caused, they are optimistic that the pandemic should be viewed as a catalyst for change. It is time to...
NOTE: This video is ONLY available to watch in selected countries and geographies Tobias Steinke (Düsseldorf, Germany), Matteo Tozzi (Varese, Italy) and Robert Shahverdyan (Hamburg, Germany) give their reactions to the publication in the New England Journal of Medicine...
The CX 2020 LIVE Vascular Access Consensus session sparked global interest, with chair Nick Inston (Birmingham, UK) and moderator Domenico Valenti (London, UK) taking questions from 17 countries, spanning South America to South East Asia. The session pinpointed the...
PatenSee has initiated a first-in-human clinical trial to assess its machine vision-based surveillance system, a press release from the company reveals. The trial, led by Benaya Rozen-zvi, director of the Institute for Nephrology and Hypertension at Rabin Medical Center...
Renal artery involvement (RAI) in endovascular aneurysm repair (EVAR) is “highly predictive of the need for postoperative and permanent dialysis,” Anastasia Plotkin (University of Southern California, Los Angeles, USA) and colleagues write in the Journal of Vascular Surgery (JVS)....
Medtronic has announced the launch of IN.PACT AV drug-coated balloon (DCB) in Japan. IN.PACT AV DCB is indicated for the treatment of obstructive lesions up to 100mm in length in the native arteriovenous (AV) dialysis fistulae in patients with...
Nicholas Inston (Birmingham, UK; moderator) is joined by Jose Ibeas (Barcelona, Spain), Panagiotis Kitrou (Patras, Greece) and Tobias Steinke (Düsseldorf, Germany), for a special Vascular News webinar called ‘WavelinQ™ 4F EndoAVF System – An attractive non-surgical AV fistula option for...
There is no evidence of a benefit from additional paclitaxel-coated balloon use compared to standard balloon angioplasty alone in the context of preserving arteriovenous (AV) fistula patency for haemodialysis, according to as-yet unpublished data from the multicentre, randomised controlled...
Merit Medical Systems recently announced the enrolment of the first patients in its Wrapsody arteriovenous (AV) access efficacy pivotal (WAVE) study of the Wrapsody endovascular stent graft, an investigational device being studied for the treatment of stenosis or occlusion within...
Nicholas (Nick) Inston calls for “more creative solutions” to vascular access challenges, commending interventional radiologists’ innovative reputation as instrumental to increasing the number of treatment approaches available to physicians. Outlining the complexities of end-stage vascular access in an ever-increasing...
Ureteral stents (hollow devices placed in the ureter - the tube between the kidney and bladder) can be used temporarily to relieve urinary obstruction in patients with kidney stones. Despite the use of antibiotics, ureteral stents often become encrusted...

Alexandros Mallios