Alio and the Hargan Group are to host a webinar “Bending the cost curve in end-stage kidney disease”, covering topics including challenges facing the end-stage kidney disease (ESKD) population and future innovation in kidney health. The webinar will take place...
The risk of major complications for people who donate a kidney via laparoscopic surgery is minimal. That is the conclusion of a 20-year Mayo Clinic (Rochester, USA) study of more than 3,000 living kidney donors, which has been published...
Transit Scientific had shared via press release successful outcomes on multiple fistula and graft cases using its XO Score sheath platform, a first-of-its-kind metal-alloy scoring, cutting, and constraining structure (CS) device, along with off-the-shelf percutaneous transluminal angioplasty (PTA) balloons. XO...
Attendees at this year’s UK Kidney Week (UKKW; 7–9 June, Birmingham, UK) heard that—based on a recent, single-centre study—peritoneal dialysis (PD) appears to be a safe and effective modality choice for patients following the loss of their kidney graft....
Scott Trerotola (University of Pennsylvania, Philadelphia, USA), who is set to be awarded a Society of Interventional Radiology (SIR) Gold Medal in June 2022, sits down with Renal Interventions to share his views on the 2019 update to the...
Funder-provider engagement and patient education are vital in growing home dialysis uptake across an entire region or country. Financial incentives or performance targets are among key options for achieving the former—while the assessment of all end-stage kidney disease (ESKD)...
Bluegrass Vascular Technologies recently announced the publication of a paper featured on the cover of the June 2022 issue of the Journal of Vascular Surgery (JVS). The paper reports the use of the company’s Surfacer system to perform an ‘Inside-Out’ procedure and obtain...
A Laminate Medical Technologies press release reports that the US VasQ external support comparative study results were presented this month for the first time globally at the 2022 Vascular Access for Hemodialysis Symposium (VASA; 9–11 June, Charleston, USA). The study...
At this year’s Vascular Access for Hemodialysis Symposium (9–11 June, Charleston, USA), Alexander Toledo (University of North Carolina, Chapel Hill, USA) asserted the advantages of selectively ligating a patient’s arteriovenous fistula (AVF) following a successful kidney transplant—citing long-term medical,...
SoniVie recently announced that on 5 May 2022 the US Food and Drug Administration (FDA) granted investigational device exemption (IDE) approval for its REDUCED1 pilot study to treat resistant hypertension patients with renal artery denervation using the company's therapeutic...
In a retrospective cohort study published in the American Journal of Kidney Diseases (AJKD), researchers have found that US adults receiving haemodialysis who are exposed to higher levels of air pollution have more heart attacks and strokes compared to haemodialysis...
It is critical that clinicians follow—or, at the very least, are aware of—their centre’s policies regarding cannulation practices. This message was delivered by Deborah Brouwer-Maier (Transonic Systems, Ithaca, USA) during a presentation at the 2022 Vascular Access for Hemodialysis...
AlloVir has announced preliminary, blinded data from an ongoing Phase 2 study of posoleucel—an investigational, allogeneic, off-the-shelf, multi-virus-specific T cell (VST) therapy for the treatment of BK viraemia in adult kidney transplant recipients. These data from the largest study...
CareDx recently announced that it plans to expand its growing multimodality portfolio with AiKidney—a new clinical decision support tool for allograft risk assessment that is in development, and includes the company’s AlloSure testing tool and other transplant metrics. This follows...
Hansa Biopharma has announced a recommendation by the National Institute for Health and Care Excellence (NICE) for its first-in-class treatment Idefirix (imlifidase) in the desensitisation of highly sensitised adult patients prior to receiving a kidney transplant from a deceased...
Artio Medical today announced the closing of US$28 million in oversubscribed Series A2 and Series A3 financing, bringing the total amount raised by the company to date to US$74 million. Funds will be used to support US commercialisation efforts for the recently cleared...
New data presented at the 2022 Vascular Access for Hemodialysis Symposium (9–11 June, Charleston, USA) have demonstrated favourable outcomes with the Flex Vessel Prep system as compared to historical data, and “really impressive” results in the cephalic arch and...

Matteo Tozzi

Having grown up and studied medicine in Rome, Matteo Tozzi is currently deputy head of the Department of Medicine and Surgery, and associate professor of vascular surgery, at the University of Insubria in Varese, Italy. His work within the...
A research team led by Kazumi Taguchi, Shuzo Hamamoto and Takahiro Yasui (Nagoya City University , Nagoya, Japan) recently undertook a clinical trial to assess whether an artificial intelligence (AI)-powered device called the Automated Needle Targeting with X-ray (ANT-X)...
Outset Medical today announced it has implemented a shipment hold on the distribution of its Tablo haemodialysis system for home use pending the US Food and Drug Administration’s (FDA) review and clearance of a 510(k) the company submitted for...
While a fourth vaccine dose does increase anti-spike immunoglobin-G (IgG) and neutralising capacity against many COVID-19 variants of concern (VOCs), some solid-organ transplant recipients may remain at a high risk for Omicron infection despite receiving vaccine boosters. This is...
Jeremy Crane (London, UK) discusses the topic of vein preservation—including its central importance to successful dialysis access creation, and practical measures for achieving it in clinical practice. The presence of patent peripheral key veins in the arm is an obvious...
Based on over four years of experience in a single centre, Robert Shahverdyan (Asklepios Klinik Barmbek, Hamburg, Germany) claims that endovascular arteriovenous fistula (endoAVF) creation “keeps future options open,” but is not a replacement for surgical fistula creation. Speaking at...
Natera today announced the presentation of data on the clinical utility of its Prospera and Renasight tests across a total of 14 sessions at the 2022 American Transplant Congress (ATC; 4–8 June, Boston, USA). This expands on 13 peer-reviewed...
With comprehensive UK Renal Registry (UKRR) data from 2020 set to be published by the UK Kidney Association (UKKA) imminently, Renal Interventions previews a handful of key talking points these figures will likely trigger. One immediate observation from the 2022...
This advertorial is sponsored by Vascular Therapies Arteriovenous fistula (AVF) maturation is a pivotal event in patients requiring haemodialysis. Maximising the number of fistulas that mature, become suitable for initial clinical use and remain suitable for sustained clinical use continues...
Highlights: Multiple new data from the Charing Cross (CX) Symposium on drug-coated balloons (DCBs) and their application in vascular access Scott Trerotola (Philadelphia, USA) discusses his thoughts on the most recent Kidney Disease Outcomes Quality Initiative (KDOQI) guideline update ...
Highlights: Multiple new data from the Charing Cross (CX) Symposium on drug-coated balloons (DCBs) and their application in vascular access Scott Trerotola (Philadelphia, USA) discusses his thoughts on the most recent Kidney Disease Outcomes Quality Initiative (KDOQI) guideline update ...
MedAlliance’s Selution SLR drug-eluting balloon (DEB) has received investigational device exemption (IDE) approval from the US Food and Drug Administration, making it the first limus DEB to be available to US patients, the company announced in a press release. The...
Sonavex has announced that it has received a US$1.7 million grant from the US National Institutes of Health (NIH) to further develop EchoGuide—a novel technology which is designed to reduce cannulation injury. The grant provides capital for ongoing research and...
Medtronic and DaVita have together announced their intent to form a new, independent kidney care-focused medical device company in an effort to enhance the patient treatment experience and improve overall outcomes. According to a joint press release, the new company will...
Hologic has received the European CE mark for two new molecular assays—Panther Fusion EBV Quant Assay and Panther Fusion BKV Quant Assay—expanding its transplant pathogen monitoring menu on the Panther Fusion system. The assays quantify the viral load of the...
VentureMed Group recently announced that it has completed enrolment of a randomised controlled trial (RCT) titled 'Flex Vessel Prep prior to PTA for the treatment of obstructive lesions in the native AVF'. This RCT was conducted to assess primary...
Sanjay Misra (Rochester, USA) discusses the need for pharmacological approaches that can improve successful, long-term outcomes with arteriovenous fistulas (AVFs) and outlines a handful of novel solutions on the horizon. In 2017, about 750,000 US patients were diagnosed with end-stage...
Three late-breaking clinical trials presented at the 59th European Renal Association (ERA) congress (19–22 May, Paris, France) have placed increased focus on the need to quickly detect and treat chronic kidney disease (CKD). Annette Bruchfeld (Karolinska Institute, Solna, Sweden), who...
X-Therma has announced that the Center for Devices and Radiological Health (CDRH) of the US Food and Drug Administration (FDA) has granted its proprietary XT-ViVo organ preservation solution and TimeSeal organ transport device Breakthrough Device status. “This milestone moves us as a...
Late-breaking trial data presented at EuroPCR 2022 (17–20 May, Paris, France) underscore the potential of renal denervation as an adjunctive therapy to treat hypertension, complementing existing first-line treatments including lifestyle modifications and medication, attendees of the conference heard. Day one...
Germany-based endovascular simulator supplier CATHI has joined forces with UK-based Vascular Simulation Solutions (VSS) to offer the world’s first online training masterclass using endovascular simulation coupled to a structured curriculum, the company said in a press release. At its...
The results of a small-scale pilot study from Asia have indicated “potentially disappointing” results with a novel drug-eluting balloon in treating dysfunctional arteriovenous access for dialysis. These findings were delivered by Tjun Tang (Singapore General Hospital, Singapore)—who also highlighted...
Invizius recently announced that it has been awarded a second Biomedical Catalyst grant (Feasibility and Primer Award) by Innovate UK to research a new field of application—peritoneal dialysis (PD)—for its H-Guard technology. The company is developing a H-Guard haemodialysis priming...
NOTE: This video is ONLY available to watch in selected countries and geographies In a late-breaking Podium 1st presentation at the 2022 Charing Cross (CX) International Symposium (26–28 April, London, UK), Andrew Holden (Auckland, New Zealand) revealed that patients...
In recognition of the fact that “too many” people in Canada are on organ waitlists, with Canada also lagging behind other high-performing countries in organ donation, the Canadian government has invested CA$2 million into two innovative organ and tissue...
Dialyze Direct has announced that its findings regarding the effect of more frequent dialysis for end-stage kidney disease (ESKD) patients in skilled nursing facilities (SNFs) have been peer-reviewed by Hemodialysis International and published in an article entitled “Post-Dialysis Recovery Time in...
Relavo has been awarded a National Science Foundation (NSF) Small Business Innovation Research (SBIR) grant worth US$1 million, which will be used to complete development and conduct safety, efficacy, and usability testing on the PeritoneX disinfection system. The PeritoneX is...
Kate Steiner (Stevenage, UK) discusses existing clinical evidence on drug-coated balloons (DCBs) in the treatment of arteriovenous access stenosis—and outlines areas where further data are still needed on how they stack up against more traditional plain-balloon techniques. Failure of maturation...
Medtronic has announced new randomised controlled data demonstrating the sustained and superior performance of the IN.PACT AV drug-coated balloon (DCB) compared to percutaneous transluminal angioplasty (PTA) through 36 months, with no difference in mortality. The data were delivered as...
The preliminary results from a clinical trial assessing a restorative haemodialysis access graft have shown promising early puncturing, patency and safety data. These findings from an ongoing first-in-human study of the Axess graft (Xeltis) are being presented for the...
Medtronic has announced that Laura Mauri has been appointed as the company’s chief scientific, medical and regulatory officer. This appointment adds to Mauri's prior responsibilities as chief clinical and regulatory officer, aligning and integrating the company's scientific, medical, clinical research...
This advertorial is sponsored by Alio Medical Owing to the various risk factors and potential complications faced by kidney disease patients undergoing dialysis treatment, new technologies that enable these patients to be monitored remotely and continuously—and ultimately managed more effectively—are...
The US Food and Drug Administration (FDA) has awarded 510(k) clearance to Fresenius Medical Care North America (FMCNA) for its Versi peritoneal dialysis (PD) cycler system—a next-generation, portable automated peritoneal dialysis (APD) system. Fresenius claims that Versi PD is “the...
A federal partnership established to help increase access to COVID-19 vaccines for end-stage kidney disease (ESKD) patients receiving dialysis was successful in reducing racial disparities in vaccination coverage, new research published in JAMA Internal Medicine has affirmed. Compared to white patients,...
Alio has announced it has received US Food and Drug Administration (FDA) 510(k) clearance for its remote monitoring system, which is intended for use by healthcare professionals to intermittently collect physiological data—including skin temperature, auscultation sound data and heart...
Fresenius Medical Care announced today that its Global Medical Office has launched the My Reason campaign to promote patient enrolment in the company's kidney-focused genomics registry, which was first introduced last year. With the “ambitious goal” of enrolling more than 100,000 participants within five...
Outset Medical has announced the release of three new data sets related to home dialysis—each of which are being presented during the ongoing National Kidney Foundation (NKF) spring clinical meetings (6–10 April 2022; Boston, USA). The results from scientific...
Baxter International has announced US Food and Drug Administration (FDA) 510(k) clearance of the company’s ST Set, intended for use in continuous renal replacement therapy (CRRT). The ST Set is a pre-connected, disposable, extracorporeal circuit that provides blood purification...
Sangamo Therapeutics has announced dosing of the first patient in the Phase 1/2 STEADFAST clinical study evaluating TX200—an investigational, wholly owned, autologous chimeric antigen receptor regulatory T cell (CAR-Treg) cell therapy product candidate for the prevention of immune-mediated rejection...
Long-term data from the first 80 patients in the SPYRAL HTN-ON MED trial have been presented during a featured clinical research session at the American College of Cardiology’s annual scientific sessions (ACC 2022, 2–4 April, Washington DC, USA). The data,...
A retrospective analysis of the US Renal Data System has found that, in patients undergoing haemodialysis treatment, a higher degree of frailty is associated with an increased timeframe for a vascular access to become functional. As such, writing in...
Nipro Medical Corporation is set to introduce its second-generation Cronus high-pressure (HP) percutaneous transluminal angioplasty (PTA) balloon catheter to the US market. Cronus HP is indicated for use in popliteal, femoral, iliac, and renal arteries, and in the treatment of...
Medtronic recently voluntarily recalled a subset of its IN.PACT Admiral and IN.PACT AV paclitaxel-coated percutaneous transluminal angioplasty (PTA) balloon catheters due to the potential for pouch damage resulting in a loss of sterility. This is according to a news...
A departure from the “extreme mantra” of Fistula First unlocks the door to a new, dynamic vision that could swing the pendulum back to increased arteriovenous graft (AVG) use. But, this hinges on shared decision-making with patients and sight...
The arteriovenous graft (AVG) for use as a dialysis conduit is a story of innovation, disappointment, intrigue, politics and hope. A recent recalibration of guidelines from “fistula first” to the “right access” may see these easy-to-use, off-the-shelf devices move...
Robotic urologic oncology surgeon Dipen J Parekh (University of Miami Health System, Miami, USA) has become the first in the USA to test a new, preoperative surgical rehearsal technology recently approved by the US Food and Drug Administration (FDA)...
Nipro Medical Corporation has announced the commercial launch of its Surdial Dx haemodialysis system—designed to create an optimal dialysis treatment experience for patients and clinicians—in the USA. Manufactured in Japan, the system draws from more than 35 years of expertise in...
Vascular Therapies today announced the closing of US$25 million in private financing. The financing in question comprised of both existing and new investors, including a Fortune 100 global healthcare company. Vascular Therapies plans to use the proceeds to further advance...
Investigators have completed enrolment in the RADIANCE-II pivotal trial of the Paradise ultrasound renal denervation (uRDN, Recor Medical) system for the treatment of uncontrolled hypertension. Subject to study outcomes, the RADIANCE-II results will be combined with the previously released data...
Kidney failure patients who wish to receive the choice of home dialysis face an unequal struggle across the UK to access such care, according to the Bridging the Gap report, which was released today by Quanta Dialysis Technologies. The...
Malignant ureteric obstruction (MUO) poses several tangible threats to cancer patients—and these threats translate, in turn, to challenges for the interventional radiologist and other treating physicians. Here, Conrad von Stempel and Tim Fotheringham (London, UK) describe a number of alternative techniques...
Data analysis from a recent clinical trial has indicated that removing a race-based adjustment in the estimation of patients’ kidney function had a small but potentially important impact on the inclusion of participants—with differing effects on Black and non-Black...
Ascend Clinical claims to have become the first customer to leverage an artificial intelligence (AI) solution with deep learning models—provided by SambaNova Systems and DeLorean AI—in an attempt to advance kidney care by classifying, tracking and transitioning renal patients...
NephroSant has today announced enrolment of the first patient in its AQUA (Assessment of QSant for underlying allograft rejection) study. Eligible participants will have undergone kidney transplantation within 90 days of enrolment—with up to 2,000 individuals being enrolled and...
As dialysis modalities go, peritoneal dialysis (PD) is currently among the more popular choices in treating kidney disease patients. For many physicians, its perceived benefits—a decreased burden on the patient and their day-to-day living arguably being the most important...
Xeltis has announced promising initial outcomes from two key vascular trials involving its restorative graft technologies. According to the company, more than 350 successful dialysis sessions have been completed in implanted patients within six months from the start of a...
Lyfebulb and CVS Kidney Care have announced 10 finalists for the 2022 Innovation Challenge: Accelerating Innovations in Kidney Disease to Improve Health Equity and Outcomes. The finalists brought forward an array of strategic, creative and scalable concepts to make kidney...
Fist Assist Devices has announced a three-year affiliation with Regional Health Care Group to commercialise and launch sales of the Fist Assist Model FA-1 device in Australia and New Zealand. The FA-1 device is a wearable, patent-protected, intermittent compression...
A retrospective review involving nearly 300 patients has concluded that precision banding as a treatment for high-flow haemodialysis accesses offers “an effective, low-morbidity approach”. The findings of the review are published in the Journal of Vascular Access (JVA). “This...
The VasQ external support device (Laminate Medical) has demonstrated long-term benefits for radiocephalic (forearm) arteriovenous fistula (AVF) creation in a retrospective analysis of 150 consecutive procedures. Robert Shahverdyan (Asklepios Klinik Barmbek, Hamburg, Germany) and Dirk Hentschel (Brigham and Women’s...
Research by the University of Leicester (Leicester, UK) into chronic kidney disease has received a major boost on World Kidney Day (10 March 2022) following a £1 million donation from long-term supporter and kidney health advocate Jimmy Mayer. This vital funding...
NephroSant has announced that the Journal of Clinical Medicine has published real-world data that provides insight into how changes in allograft health are reflected in specific ranges of QSant scores. QSant is a non-invasive home collection that analyses biomarkers of...

Charmaine Lok

Equally at home on the ward seeing patients, at study sites conducting research, and travelling the world for voluntary medical missions, Charmaine Lok has engaged in all aspects of the modern medical profession. Lok is a nephrologist and clinician...
Diality has announced the close of a US$24 million Series B2 investment round. The Series B2 round of funding will be used for activities to support US Food and Drug Administration (FDA) 510(k) clearance of the company’s versatile haemodialysis system—including preparing...
The concept of dedicated vascular access centres fuels a turbocharged Texan tussle with Karl Illig (Flow Vascular Center, Houston, USA) taking on Eric Peden (Houston Methodist Hospital, Houston, USA) in a no-holds-barred debate on how best to deliver longitudinal...
The second edition of Renal Interventions homes in on multiple key issues currently rousing the kidney disease management community, including: The promise offered by recent xenotransplantation procedures in tackling global donor organ shortages An in-depth look at the evolving...
The second edition of Renal Interventions homes in on multiple key issues currently rousing the kidney disease management community, including: The promise offered by recent xenotransplantation procedures in tackling global donor organ shortages An in-depth look at the evolving...
Baxter International has announced new data indicating the use of its Sharesource remote patient management platform with an automated peritoneal dialysis cycler may improve the clinical effectiveness of dialysis care for kidney patients by extending their time on home therapies by...
Dialysis patients who received an adenovirus vector-based COVID-19 vaccine (Johnson & Johnson) were found to have similar rates of breakthrough infection, hospitalisation and mortality as dialysis patients who received an mRNA-based vaccine (Pfizer/BioNTech), according to a DaVita Clinical Research...
Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different spatial scales. Tested in mouse tissues, the method,...
SyMap Medical has announced that it has completed enrolment of the SMART study, which will evaluate the safety and efficacy of targeted renal denervation (RDN) using the SyMapCath I system for the treatment of uncontrolled hypertension. According to SyMap, this...
Cibiltech has announced that the first patient has been enrolled in the CIBIL (Clinical impact of the iBox as an early intervention tool) study, a prospective randomised controlled trial to assess the use of a software predicting allograft survival...
The interim results of an ongoing clinical study of PatenSee's contactless imaging device for the early detection of vascular access stenosis in dialysis patients were recently shared in a poster presentation at the World Congress of Nephrology (WCN'22; 24–27...
Humacyte today announced that five-year data from a phase 2 clinical trial of patients receiving the investigational Human Acellular Vessel (HAV) for arteriovenous (AV) access in haemodialysis have been published in the European Journal of Vascular and Endovascular Surgery companion...
Charing Cross (CX) chair Roger Greenhalgh welcomes the vascular community to this year's symposium, due to be held 26–28 April in London, UK, and virtually. To read the preliminary programme and register visit cxsymposium.com.
Bio-Techne has announced an agreement with Thermo Fisher Scientific to exclusively complete the development of and commercialise the ExoTRU kidney transplant rejection test developed by Exosome Diagnostics, a Bio-Techne brand, a press release claims. ExoTRU is a non-invasive, multigene, urine-based...
As per a clinical study involving more than 2,300 adult patients, a second kidney transplant is likely to offer improved survival outcomes when compared to shifting over to dialysis treatment in people whose first kidney graft has stopped functioning...
A multicentre experience with the 4 French (4Fr) WavelinQ endoAVF system (BD) has found that the device is safe and effective, bolstering existing evidence that it could offer an alternative option to surgically created arteriovenous fistulas (AVFs) in the...
Natera has announced the results of a large clinical experience study confirming the "strong performance" of its Prospera donor-derived cell-free DNA (dd-cfDNA) test in assessing rejection for kidney transplant patients. The study, published in Transplantation Proceedings, reports the real-world impact of dd-cfDNA...
Transplantation discrepancies between Black and white patients have been found to contribute significantly to differing survival rates for childhood-onset kidney failure across the two racial groups. Reporting these findings in the Journal of the American Society of Nephrology (JASN),...
DaVita Kidney Care has announced the appointment of Mihran Naljayan—a clinical associate professor at LSU School of Medicine (New Orleans, USA) who is board-certified in nephrology and hypertension through the American Board of Internal Medicine—as its new chief medical officer...
In light of recent and upcoming developments in the space, Vinson Wai-Shun Chan and Tze Min Wah (Leeds, UK) explore the evidence and latest progress in renal tumour biopsy (RTB), and discuss the treatment of small renal masses (SRMs)...
CloudCath announced today it has received US Food and Drug Administration (FDA) clearance for the CloudCath system—which the company claims is the world's first data-driven, cloud-based, remote monitoring platform for peritoneal dialysis (PD) patients. The company is planning a...
Far infrared radiation (FIR) has demonstrated no haemodynamic changes in the arteriovenous fistulas (AVFs) of haemodialysis patients, despite prior contradicting research. This is the key finding of a study published in the Journal of Vascular Access by Emilie K...
Screening protocols to determine who qualifies for ‘compassionate dialysis’ in hospitals with high numbers of uninsured patients are contributing to increased strain on the emergency room (ER), as measured by how long ER patients are waiting to be seen...
Trestle Biotherapeutics has entered into a license agreement with Harvard University (Cambridge, USA). Under the agreement, Trestle will commercialise a suite of stem cell- and 3D biofabrication-based regenerative medicine technologies developed at Harvard’s Wyss Institute for Biologically Inspired Engineering,...
Fresenius Medical Care North America (FMCNA) has become the latest company to announce partnerships with nephrology providers via the new Kidney Care Choices (KCC) models—first announced by the Centers for Medicare and Medicaid Services (CMS) in 2019, and formally...
Arteriovenous fistula (AVF) access is one of the key areas that is set to receive a boost following MedAlliance’s acquisition of its partner MDK Medical—according to a company press release. MDK Medical has previously worked closely with MedAlliance in...
A systematic review published in the Journal of Vascular Access (JVA) has illuminated haemodialysis patients’ views and experiences of arteriovenous access cannulation, concluding that many patients learn to tolerate its unpleasantness out of a sense of necessity, with feelings...
Peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual has been published in the American Journal of Transplantation. This publication was recently announced by the University of Alabama at Birmingham (UAB) Marnix E...
The US Food and Drug Administration (FDA) has issued two final guidances providing recommendations for including patient perspectives in medical device clinical studies.   As per an FDA press release, the finalised version of the first of these two guidance...
Fresenius Medical Care North America (FMCNA) has announced that its KidneyCare:365 chronic kidney disease (CKD) health programme has been awarded Population Health Program (PHP) accreditation by the National Committee for Quality Assurance (NCQA). According to a company press release, KidneyCare:365...
As per an announcement on the company’s LinkedIn page, InnAVasc Medical has been granted US Food and Drug Administration (FDA) permission to commence the third phase of enrolment for its pivotal clinical study. “This is a big step forward to...
Concept Medical has shared the latest update from its IMPRESSION (Sirolimus-coated balloon angioplasty versus plain balloon angioplasty in the treatment of dialysis access dysfunction) randomised controlled trial (RCT), as it crosses the 50% enrolment mark. The IMPRESSION trial enrolled its...
NextKidney BV has announced the acquisition of Dialyss Pte Limited from 1 January 2022. According to a press release, this marks a major milestone towards the commercialisation of the first truly portable, sorbent-based haemodialysis device, the Neokidney—which the company...
Fluidx Medical has announced in a press release that its GPX embolic device was used to effectively devascularise a large renal tumour with multiple feeding vessels as part of a multicentre clinical trial. "This could have been a challenging case...
DaVita has announced the acquisition of transplant software company MedSleuth, which works with US transplant centres to improve experiences and outcomes for kidney and liver transplant patients. With this acquisition, DaVita is deepening its efforts to fuel transplant innovation, underscoring...
Pathfinder Medical, which has developed a proprietary technology to guide and accurately align catheters in endovascular procedures allowing clinicians to make connections across blood vessels in the body without the need for open surgery, has announced securing £8.5 million. The...
Cancer, infections and heart disease pose the greatest risk to kidney transplant recipients—not organ rejection—according to a recently published Mayo Clinic study. Researchers discovered that recipient death due to factors other than organ rejection is the leading cause for...
Anais Medical, a new company founded by Parc Taulí Research and Innovation Institute (I3PT) and led by José Ibeas (nephrologist at Parc Taulí University Hospital, Barcelona, Spain), intends to develop practical educational material that uses realistic models and simulations,...
There are some very serious risks associated with forgotten ureteric JJ stents. David Maudgil, a consultant interventional radiologist at Wexham Park Hospital, Frimley Health Foundation Trust (Slough, UK), outlines why and when these devices are used, explains the risks...
Fresenius Kidney Care and Biim Ultrasound AS have announced an agreement to expand use of Biim's innovative ultrasound system for assisting needle cannulation prior to dialysis treatment. Fresenius successfully piloted the use of Biim's ultrasound system at more than two dozen dialysis...
The National Kidney Foundation (NKF) has announced the recipients of two of its most prestigious awards in the field of nephrology, with Bernard Jaar, a practising nephrologist at the Johns Hopkins School of Medicine in Baltimore, USA, and Cheyenne Fasce, a...
Attempts to optimise the current state of play in vascular access for dialysis patients—from deployment of drug-coated balloons (DCBs) to more novel vein dilation technologies—piqued the interest of Renal Interventions readers throughout 2021. An in-depth interview with pioneering vascular...
Home haemodialysis provider Dialyze Direct has announced the acquisition of Renew Dialysis, a regional provider of on-site dialysis services in skilled nursing facilities (SNFs), with eight locations in Ohio and one in Virginia, that was co-founded by Saber Healthcare...
The Getting It Right First Time (GIRFT) national report on renal medicine represents a “call to action” for the UK renal community, and provides greater focus in driving quality improvement across care pathways for kidney disease. These were among...
Kidney transplant recipients tend to mount impaired antibody responses against emerging SARS-CoV-2 variants after standard two-dose COVID-19 vaccination, according to a study published in the Clinical Journal of the American Society of Nephrology (CJASN). The research shows this is also...
Hansa Biopharma recently announced that the first patient has been enrolled in its CONFIDES trial—a US pivotal, open-label, randomised controlled study—at the Columbia University Medical Center (New York, USA). The CONFIDES trial is evaluating the drug imlifidase as a potential desensitisation...
Fresenius Medical Care has announced the launch of Carrie, a custom-built mobile application intended to connect, inform and support Fresenius Kidney Care nurses and clinical teams in the Asia Pacific (APAC) region. Named ‘Carrie’ in recognition of the “limitless...
Zynex Monitoring Solutions recently reported it has started enrolment in a haemodialysis clinical trial with its CM-1500 fluid monitoring system. The study, conducted at DaVita Clinical Research clinics, is aimed at further characterising changes in the device's patented Relative...
Researchers from the University of Alabama at Birmingham (UAB; Birmingham, USA) and US firm Endomimetics are working to develop a long-sought-after, effective therapy that will promote healthy maturation in arteriovenous fistulas (AVFs)—and recently reported preclinical progress on this front...
Xeltis has announced initiation of a clinical trial evaluating Axess, which it claims is the first ever restorative synthetic haemodialysis access graft. Several patients with kidney failure or advanced kidney disease requiring dialysis have already been successfully implanted as...
A single-centre, retrospective, comparative study, which was presented at the July 2021 Journal of Vascular Surgery (JVS) Journal Club (14 July, online), has found that percutaneous arteriovenous fistula (pAVF) creation may be associated with lower rates of complication relating...
Fist Assist Devices has announced that it recently received Breakthrough Device designation from the US Food and Drug Administration (FDA) for its Fist Assist Model FA-1 device. According to the company, the FA-1 is the world’s first wearable device for...
Arteriovenous fistulas (AVFs) are widely considered to be the holy grail in dialysis access, providing a more long-term solution than synthetic arteriovenous grafts (AVGs) or central venous catheters (CVCs), with a reduced risk of complications. However, these benefits only...
DaVita has recently become the first kidney care provider to completely power its North American operations with renewable energy, according to a press release from the company. DaVita achieved this goal, which it set in 2019, by contracting with Longroad...
Video-based telemedicine is used to facilitate care across all stages of chronic kidney disease (CKD) and has evolved in recent years to be less reliant on specialised equipment, allowing patients to receive kidney care in a location of their...
 Nicholas Inston (consultant vascular access and renal transplant surgeon, Birmingham, UK) discusses the crucial care interventional radiologists provide for renal patients with Ian Mcafferty (consultant interventional radiologist, Birmingham, UK, and immediate past president of the British Society of Interventional...
 Nicholas Inston (Birmingham, UK) talks to CX about the challenges in creation, maintenance and salvage of vascular access in patients with end stage renal disease. Inston highlights the many innovations and technologies that have come to the forefront in recent...
 Alexandros Mallios (Paris, France) and Robert Shahverdyan (Hamburg, Germany) talk to Vascular News about some of the benefits of the Ellipsys™ Vascular Access System (Medtronic), how it compares to more traditional fistula creation techniques, and the key steps for...
Cleaning and low-level disinfection (LLD) effective against bloodborne pathogens are safe and sufficient procedures for disinfecting ultrasound transducers used in percutaneous procedures—this is according to an intersocietal position statement recently issued by the American Institute of Ultrasound in Medicine...
NYU Langone Health has performed a second successful investigational xenotransplantation procedure using a genetically engineered pig kidney. This second surgery is a sign of continued progress toward a potential alternative supply of life-saving organs, according to a press release. Leading...
Huge strides have been made in preventing contrast-associated acute kidney injury among patients undergoing percutaneous coronary intervention (PCI) and other interventional procedures in recent decades, Roxana Mehran (Icahn School of Medicine at Mount Sinai, New York, USA) tells Cardiovascular...
SyMap Medical has announced the completion of a financing round that will be used to accelerate global clinical trials for the company’s renal mapping and selective renal denervation systems. The financing round of nearly US$100 million was led by Primavera...
Arrow International has recalled its Arrow-Trerotola over-the-wire 7Fr percutaneous thrombolytic device (PTD) kits, which are used to remove clots in adult patients who have arteriovenous fistulas (AVFs) and synthetic dialysis grafts. The recall has been attributed to the risk of the orange...
Alio has announced a partnership with Lifeline Vascular Care in support of patients living with end-stage renal disease (ESRD). Alio leverages artificial intelligence (AI) and the company’s SmartPatch sensor technology to non-invasively monitor vascular access health and other chronic...
 The Amplifi Vein Dilation System (Artio Medical) is an innovative device designed to dilate arm veins in preparation for arteriovenous fistula (AVF) surgery using rapid, non-pulsatile venous blood flow. Surendra Shenoy, M.D. (a vascular surgeon with specialist interest in...
Artio Medical has announced that full results from its first-in-human clinical study of the Amplifi vein dilation system were presented at the 2021 VEITHSymposium (16–20 November, Orlando, USA and virtual) by Surendra Shenoy, associate professor of surgery in the Washington University School...
An observational study published in the Journal of the American Society of Nephrology (JASN) has identified a “promising” histological marker for determining kidney transplant failure. A collaboration between Kyoto University and Akita University in Japan—led by Motoko Yanagita, a professor...
University of Maryland Medicine—which is comprised of the University of Maryland Medical System (UMMS) and the University of Maryland School of Medicine (UMSOM)—has announced that it will end the use of a long-standing clinical standard for measuring kidney function...
Dialysis patients who received mRNA COVID-19 vaccines had a lower risk of COVID-19 diagnosis post-vaccination, and were less likely to be hospitalised or die following breakthrough infection compared to unvaccinated patients. That is according to a study announced today...
RenalSense recently announced it has secured US$14 million to bolster the global commercialisation of its current product, the Clarity RMS, expand clinical validation to additional clinical settings, and advance the release of its next-generation products based on its sensor platform. The...
An updated risk score to predict possible contrast-associated acute kidney injury (CA-AKI) among patients undergoing percutaneous coronary intervention (PCI) has been presented by Roxana Mehran (Icahn School of Medicine at Mount Sinai, New York, USA) at the American Heart...
New technologies intended to improve the often-mixed outcomes associated with arteriovenous grafts (AVGs) for haemodialysis access were on display at this year’s Vascular Access Society of Britain & Ireland scientific meeting (VASBI; 16–17 September 2021, virtual). In addition to...
There are several different types of dialysis treatment available to kidney disease patients—with the three major players, in-centre haemodialysis (ICHD), home haemodialysis (HHD) and peritoneal dialysis (PD) all holding their own benefits and drawbacks. Mark Lambie, a senior reader...
Simulations Plus has announced that its DILIsym Services division has released RENAsym version 1A, the first version of its novel quantitative systems toxicology (QST) software for predicting and investigating drug-induced kidney injury. RENAsym modelling supports key drug development decisions by predicting potential...
Baxter Asia Pacific (Baxter) has announced the launch of My Kidney Journey—a comprehensive online portal intended to support patients living with chronic kidney disease (CKD) in the Asia Pacific (APAC) region. CKD is becoming more prevalent in countries across Asia and continues to be a...
Fresenius Medical Care recently presented its advances in home dialysis solutions at the China International Import Expo (CIIE) in Shanghai, China. The company showcased new digitalised options that enable patients with end-stage renal disease (ESRD) to perform dialysis in...
Early data have indicated that a national project, dubbed MAGIC (Managing access by generating improvements in cannulation), has improved cannulation techniques of haemodialysis accesses in UK centres. Catherine Fielding, a haemodialysis nurse and trainee advanced clinical practitioner (ACP) at...
People with kidney failure who are on dialysis or who have received a kidney transplant face a higher risk of dying from COVID-19—and new research has revealed that these individuals have profound immune system-related differences compared with people with...

Alexandros Mallios

Born and raised in the small lakeside city of Kastoria in northern Greece, Alexandros Mallios’ 15-year journey as a vascular surgeon has seen him complete a year of national service in the Greek military, travel to far-flung parts of...
The National Kidney Foundation (NKF) has announced the appointment of three new members to its national Board of Directors. The new members, Hubert L Allen (Chicago, USA), Renée Richardson Gosline (Cambridge, USA) and Alison Steiber (Shaker Heights, USA), were nominated and approved at...
OrganOx, the producer of the 'metra' normothermic machine perfusion (NMP) product, has announced the completion of a £6.4 million equity fundraise. The fundraise was led by Oxford Investment Consultants and supported by both existing and new shareholders. According to a...
 The upcoming Controversies in Dialysis Access (CiDA) meeting in Dallas, Texas is stepping up the scrutiny on the controversies and questions currently igniting the dialysis community, Bart Dolmatch (Portola Valley, USA) tells Renal Interventions at the Paris Vascular Insights...
New research presented at the American Society of Nephrology (ASN) Kidney Week (2–7 November 2021, virtual) indicates that substantial discrepancies exist between two major tools used to assess kidney function—estimated glomerular filtration rate (eGFR) and measured glomerular filtration rate...
The Ellipsys vascular access system (Avenu Medical/Medtronic) can be used to easily and safely create durable percutaneous arteriovenous fistulas (pAVFs) for haemodialysis—with new, long-term data suggesting it offers an “excellent alternative” to AVF creation via surgical procedures in end-stage...
The results of several high-impact clinical trials with the potential to impact kidney-related medical care in the future were presented at this year’s American Society of Nephrology (ASN) Kidney Week (2–7 November 2021, virtual). Highlights from this session included...
Randomised placebo-controlled trials show consistently that renal denervation provides significant reduction in ambulatory and office blood pressure, the findings of a systematic review and meta-analysis suggest. Findings of the paper, authored by Yousif Ahmad (Yale School of Medicine, Yale University,...
Six-month outcomes from the randomised RADIANCE-HTN TRIO trial, comparing endovascular ultrasound renal denervation to a sham procedure for treatment-resistant hypertension, demonstrate the additional effects of pharmacologic intervention with maintenance of a blood pressure-lowering effect of renal denervation at six...
Medtronic today announced findings from a new study of patient preferences for the treatment of hypertension. The findings are set to be presented during the “What's Novel in Interventional Hypertension” session at the 33rd Transcatheter Cardiovascular Therapeutics annual meeting (TCT...
At the 12th Congress of the Vascular Access Society (VAS; 6–9 April 2021, online), Ramon Roca-Tey, senior consultant in nephrology at the Fundación Sanitaria Mollet’s Hospital de Mollet in Barcelona, ​​Spain, and president of the Spanish Multidisciplinary Group for...
Natera has announced initial results from the global, multicentre, prospective Trifecta study, which assessed its Prospera with quantification test for kidney transplant rejection and was led by Phil Halloran, director, Alberta Transplant Applied Genomics Centre (Edmonton, Canada). "These new data from the Trifecta study...

Renal Interventions 1 – US

Renal Interventions debuts with a diverse range of hot topics and leading insight from the kidney care field, including: The introduction of a new, race-free approach to diagnosing kidney disease Highlights from the 2021 Vascular Access Society of Britain &...

Renal Interventions 1 – EU

Renal Interventions debuts with a diverse range of hot topics and leading insight from the kidney care field, including: The introduction of a new, race-free approach to diagnosing kidney disease Highlights from the 2021 Vascular Access Society of Britain...
Difficulties in cannulation are currently as pressing as any other challenge facing patients who undergo device-enabled arteriovenous fistula (AVF) creation for dialysis. This was a central message presented by Neghae Mawla (Dallas Nephrology Associates, Dallas, USA) at the Paris...
Procyrion has announced the presentation of studies at the Transcatheter Cardiovascular Therapeutics annual meeting (TCT 2021, 4–6 November, Orlando USA and virtual) relating to its Aortix percutaneous mechanical circulatory support device. The presentations include a spotlight on the company's...
Outset Medical has announced that its Tablo haemodialysis system has received the first ever approval from the Centers for Medicare & Medicaid Services (CMS) for a Transitional Add-on Payment Adjustment for New and Innovative Equipment and Supplies (TPNIES). This pioneering...
In the future, a global approach to help standardise clinical practice guidelines for kidney disease may be the ideal way forward. This was the closing message from Charmaine Lok (University of Toronto, Toronto, Canada) following a session at the...
Twelve-month results from a first-in-human study of the Wrapsody cell-impermeable endoprosthesis (Merit Medical Systems) for the treatment of access circuit stenosis in haemodialysis patients are “very encouraging”. This is according to James Gilbert, a consultant transplant and vascular access...
The Centers for Medicare & Medicaid Services (CMS) is taking action to close health equity gaps by providing Medicare patients living with end-stage renal disease (ESRD) with greater access to care, according to a press release. Through the ESRD...
VenoStent has announced successful enrolment in its initial feasibility clinical trial. The clinical trial is testing the safety and efficacy of its 3D-printed bioabsorbable wraps in humans—a new methodology to improve surgical outcomes for haemodialysis patients. Enrolment was completed for...
The first investigational transplantation of a genetically engineered, non-human kidney to a human body was recently completed at NYU Langone Health, New York, USA—marking a major step forward in potentially utilising an alternative supply of organs for people facing...
Strive Health has announced Strive Care Partners (SCP)—a dedicated platform that enables nephrologists to share and succeed in global risk contracts with payors, according to a press release. Strive Care Partners will benefit patients with chronic kidney disease (CKD) and...
Quanta Dialysis Technologies announced today the results of the UK Dialysis Patient Experience Survey, showing the wide variance in care experienced by UK dialysis patients, as well as challenges faced in assessing self-care and home haemodialysis (HHD).  The survey revealed: ...
Despite the well-known obstacles, it is time for a prospective, randomised clinical trial comparing percutaneous ablation (PA) and partial nephrectomy for the treatment of small renal cell carcinomas—and re-thinking the common practice of watching and waiting, rather than intervening,...
There are multiple barriers to home dialysis initiation, and these disproportionately affect vulnerable populations. Current solutions need to be scaled up, with particular emphasis on educating physicians on home dialysis, improving modality education, increasing support for patients and families,...
Medtronic has announced receipt of a CE mark for its Hugo robotic-assisted surgery (RAS) system, authorising the sale of the system in Europe. This CE mark approval is for urologic and gynaecologic procedures, which make up about half of all robotic...
Despite an older dialysis population, the proportion and survival of arteriovenous fistulas (AVFs) in Danish dialysis patients has not changed over a 39-year period. This is the main conclusion of a national cohort study published online in The Journal...
Journey Biosciences—a biotechnology company with a proactive diagnostic screening technology for high-risk kidney complications associated with diabetes, has announced its company launch, and the introduction of its flagship product, NaviDKD. NaviDKD is a diagnostic screening technology that analyses blood-based predictive...
Several subgroups of patients treated with the IN.PACT AV drug-coated balloon (DCB; Medtronic) for arteriovenous fistulas (AVFs) demonstrated a “statistically significant” higher rate of target lesion primary patency (TLPP) compared to those who underwent standard percutaneous transluminal angioplasty (PTA)...
Preliminary clinical results from a first-in-human study assessing the Amplifi vein dilation system (Artio Medical) were presented at this year’s Vascular InterVentional Advances conference (VIVA; 4–7 October 2021, Las Vegas, USA). Data were presented by Surendra Shenoy—an associate professor of...
ReCor Medical has announced that its Paradise ultrasound renal denervation system is now available for the treatment of uncontrolled hypertension in Germany. The first hospitals performing the procedure commercially are Heart Center Leipzig, Leipzig and Saarland University Hospital, Homburg/Saar. “Despite...
Fresenius Medical Care North America (FMCNA) has announced three key clinical leadership appointments to help drive priorities, including improving patient outcomes, adopting connected health technologies to support home dialysis and increasing access to transplantation, according to a company press release. Kathleen...
NOTE: This advertorial is ONLY available to watch in selected countries and geographies This advertorial, sponsored by BD, is intended for readers in the EMEA region only. Rethink fistula creation and maintenance with Tobias Steinke, Ounali Jaffer, Panagiotis Kitrou and...
Merit Medical Systems has announced positive results from a prospective, observational, first-in-human study to evaluate the safety and effectiveness of Wrapsody—a self-expanding, cell-impermeable endoprosthesis designed for the treatment of arteriovenous (AV) fistula access circuit stenosis and AV graft access...
Bluegrass Vascular Technologies (Bluegrass Vascular) announced today that the Centers for Medicare & Medicaid Services (CMS) has finalised a new Healthcare Common Procedure Coding System (HCPCS) code and New Technology Ambulatory Payment Classification (APC) assignment for use of the...
Following the release of the European Society of Hypertension’s (ESH’s) updated position paper on renal denervation, Konstantinos Tsioufis, professor of Cardiology at the University of Athens, Athens, Greece and immediate past president of ESH, discusses the use of renal...
DaVita Kidney Care has marked Nephrology Nurses Week by announcing the appointment of Tina Livaudais as its chief nursing officer (CNO). Livaudais most recently served as vice president of clinical services for the National Hospital Services Group, overseeing more...
An implantable bioartificial kidney device (iBAK)—which promises to free kidney disease patients from dialysis machines and transplant waiting lists—has taken another step towards becoming a reality after being awarded a US$650,000 prize from KidneyX. The device’s creator, the Kidney...
Natera has announced the launch of Prospera with quantification, the only cell-free DNA (cfDNA) test for kidney rejection that provides three values—the quantity of donor-derived cfDNA (dd-cfDNA), fraction of dd-cfDNA, and total cfDNA—on every report. Combining these three metrics...
European Society of Hypertension (ESH), the leading hypertension (HTN) society in Europe, presented an updated position paper on renal denervation (RDN) during the eighth pre-ESH congress satellite symposium (10–11 September; Athens, Greece). The paper was recently published in the...
Black transplant recipients and patients who received kidneys from Asian donors had a significantly higher risk of their kidney grafts failing within seven years, according to a new study presented at the European Society for Organ Transplantation Congress (ESOT...
The number of solid organ transplants performed during the first wave of the COVID-19 pandemic in 2020 plunged by nearly a third (31%) compared to the previous year, according to a new global study presented at the European Society...
ImpediMed, an Australia-based medical technology company using bioimpedance spectroscopy (BIS) to generate powerful data to improve patient health, has announced that the Sozo digital health platform has been designated as a Breakthrough Device by the US Food and Drug...
Rubicon Founders has announced the launch of Evergreen Nephrology—a company partnering with nephrologists to transform kidney care, according to a press release. Evergreen is focused on transforming kidney care for patients across the USA and believes that nephrologists are...
Fresenius Medical Care North America (FMCNA) and Cigna have announced an expansion of their national effort to improve health outcomes and lower the cost of care for people living with kidney failure, or end-stage renal disease (ESRD). The new...
A patient-level meta-analysis of randomised controlled trials (RCTs) has shown that drug-coated balloons (DCBs) were “consistently favoured” over percutaneous transluminal angioplasty (PTA) to prolong target lesion primary patency and access circuit primary patency in the treatment of dysfunctional haemodialysis...
While the average time spent on a waitlist for a kidney transplant in South Carolina is 42 months, changes to the U.S. kidney allocation system could result in reduced access to kidney transplants and further time on waiting lists,...
Fist Assist Devices has announced that data associated with the p-FACT cohort, a subset of the recently completed, non-significant risk Fist Assist clinical trial (FACT trial) that focused on vein dilation in stage four patients with chronic renal failure,...
A pilot study has begun to assess the antibody response to a third dose of an authorised COVID-19 mRNA vaccine in kidney transplant recipients who did not respond to two doses of the Moderna or Pfizer-BioNTech COVID-19 vaccine. The...
The Society for Cardiovascular Angiography and Interventions (SCAI) has released a proceedings document outlining the possible role of renal denervation (RDN) as a therapeutic option to complement medical therapy and lifestyle interventions for patients with uncontrolled hypertension. The document...
Fist Assist Devices has just announced completion of the FACT trial, which evaluated the use of an intermittent pneumatic compression device, model FA-1, to promote vein dilation in patients with kidney disease. The trial’s results suggest the device could...
Through collaboration with Amazon Web Services (AWS), Baxter International is using cloud technology solutions to accelerate its company-wide digital transformation. According to a Baxter press release, this transformation will take place across three strategic areas—developing new digital health solutions...
Failure of home haemodialysis (HHD) treatment, defined as a return to in-centre haemodialysis (ICHD), has been associated with a “significant increase” in mortality when compared to continued HHD—a trend that was observed in both the early (first 30 days...
Artio Medical announced today it has completed enrolment in its first-in-human study evaluating the Amplifi vein dilation system. In the study, five patients were treated by Adrian Ebner, head of the Cardiovascular Department at Sanatorio Italiano Hospital in Asunción, Paraguay. "I am very...
The National Kidney Foundation (NKF) has released a position paper, developed by 16 nephrology experts from 13 institutions, with recommendations designed to navigate future research and innovation addressing the most pressing barriers to kidney transplant access, organ availability, and long-term...
A large, single-centre retrospective study has revealed the risk of acute kidney injury (AKI) following pharmacomechanical thrombolysis (PMT) for lower extremity deep vein thrombosis (DVT) is as high as 22%. PMT is an established treatment for selected patients with acute...
A retrospective analysis published in the Journal of Vascular Access (JVA) has shown that the oversized balloon angioplasty technique to assist arteriovenous (AV) fistula maturation is safe and effective—and allows cannulation of the fistula within hours or days of...
Polar Speed—UPS Healthcare's UK operation—has announced a five-year commercial agreement with Fresenius Medical Care to provide warehouse and transport solutions for the delivery of renal services and treatments to patients, and customers, in the UK. Through this agreement, Polar Speed...
A nationwide survey distributed among 150 randomly selected dialysis facilities in the USA has found that a “substantial proportion” of patients receiving in-centre haemodialysis are hesitant about seeking a COVID-19 vaccination. Notably, this proportion is still thought to be...
Results from a new study support the validity of a score that considers various patient-reported measures and preferences for assessing health-related quality of life, and promoting patient-centred care, in individuals with kidney failure. The study appears in the most...
Hansa Biopharma has announced three-year follow-up data on graft survival rates in crossmatch positive patients who received imlifidase prior to kidney transplantation. As reported in the article, which the company states has been accepted for publication in the American...
Multidisciplinary panel of UK experts agrees on roadmap and optimal stepwise application of interventions for symptomatic AVF stenoses in haemodialysis patients. Ounali Jaffer (London, UK) talks to Renal Interventions about the team's recent publication in CVIR.
Diaverum, a global renal care service provider, has launched its first ever holiday dialysis travel guide in an effort to “empower renal patients worldwide to live out their dreams of travel, whilst maintaining access to the vital, life-saving treatments...
 Nicholas Inston (Queen Elizabeth Hospital Birmingham, Birmingham, UK), secretary of the Vascular Access Society (VAS) and chairman of the editorial board for Renal Interventions interviews Christoph Wanner (University Hospital Würzburg, Würzburg, Germany), president of the European Renal Association (ERA). They talk...
With national guideline writers in the UK and other countries weighing up the role of the Kidney Failure Risk Equation (KFRE) from a renal referrer’s perspective, including in primary care, new research finds that both the four- and eight-variable...
This year's American Association of Kidney Patients (AAKP) policy summit highlighted the challenges and opportunities for researchers and companies involved in safely bringing new, or expanding, kidney care innovations to consumer markets. The consistent messages shared among all 2021...
Alio Medical, a wearable technology company enabling insights through clinical grade real-time data, has announced the close of a financing round totalling US$20 million. The company says it will use the funding to conduct clinical studies on expanded indications and...
DaVita Kidney Care has announced the expansion of its home kidney care programme to include the HomeChoice Claria Automated Peritoneal Dialysis (APD) system, enabled by Sharesource remote patient monitoring from Baxter International. For many patients with kidney failure, choosing a...
DaVita Kidney Care has launched virtual support groups through DaVita Care Connect, a mobile health platform designed for home dialysis patients, which the company says aims to help create a community for those undergoing treatment at home. "Patients treating at...
Kidney Care Partners (KCP)—a US multi-stakeholder coalition representing patient advocates, physician organisations, health professional groups, dialysis providers, researchers and manufacturers—has relaunched the Kidney Care Quality Alliance (KCQA) in an effort to develop meaningful measures to evaluate facility-level quality performance,...
Quanta Dialysis Technologies has announced that it has raised US$245 million in an oversubscribed and upsized Series D financing round—the largest private funding round for a dialysis device company in history, according to a press release from the firm—which...
The largest randomised controlled trial comparing long-term surgical outcomes between two different anaesthetic techniques, the ACCESs study, has just launched in the UK, to test whether regional, when compared to local, anaesthesia during arteriovenous fistula (AVF) creation will confer...
Despite the device demonstrating no serious adverse events (SAEs) in a preliminary safety study, researchers believe further enhancements are needed to improve the outcomes associated with the automated wearable artificial kidney (AWAK)-PD system (AWAK Technologies) for peritoneal dialysis patients....
Fist Assist Devices has received US Food and Drug Administration (FDA) 510(k) clearance for use of the Fist Assist FA-1 device in the USA as an arm massage and increased vein circulation device, and has commenced marketing the Fist...
Medtronic has announced the first patient procedure with the Hugo robotic-assisted surgery (RAS) system. The robotic prostatectomy was performed by urological surgeon Ruben Olivares (Clínica Santa Maria, Santiago, Chile) and, according to a company press release, marks the beginning of the Hugo...
Concept Medical has provided an update on the progress of the IMPRESSION (sirolimus-coated balloon angioplasty versus plain balloon angioplasty in the treatment of dialysis access dysfunction) trial—a prospective, multicentre, two-arm parallel group, randomised clinical study designed to assess the efficacy of...
New research indicates that patients with kidney failure who receive care at for-profit dialysis facilities are less likely to be referred for kidney transplants than those receiving care at non-profit facilities. These findings appear in the Clinical Journal of...
Dialysis provider US Renal Care recently announced it has finished administering a second round of mRNA vaccines to ensure better protection against COVID-19 for thousands of vulnerable patients on dialysis. "The administration of vaccines to our patients and their caregivers...
Monogram Health, a benefit management and care delivery company attempting to transform care for individuals with chronic kidney disease (CKD) and end-stage renal disease (ESRD), has announced the closing of a Series B funding round worth US$160 million. The...
A new study, published online in The Journal of Vascular Access (JVA), suggests that arteriovenous fistulas (AVFs) contribute to higher survival of haemodialysis patients with COVID-19. Authors Ahmet Murt (Istanbul University-Cerrahpasa, Istanbul, Turkey) and colleagues urge that end-stage renal...
When it comes to treating steal syndrome, the extent to which the dialysis patient in question is displaying symptoms—as well as their flow rate and the location of their anastomosis—should all be taken into consideration. This concept was presented...
Baxter International, a global innovator in renal care, has announced new data showing expanded haemodialysis (HDx) therapy enabled by the company's Theranova dialyser may reduce cardiovascular events by 35% and hospitalisation rates by 18%. This data comes from a...
Tackling the main culprit, stenosis in the arteriovenous anastomosis and outflow veins, with balloon angioplasty before it is “too late” can boost maturation rates in slow-to-mature arteriovenous (AV) fistulas. Robert Jones, consultant interventional radiologist at the Queen Elizabeth Hospital...
Fresh evidence on the usefulness of sonography to ease the burden of lung congestion in haemodialysis patients and “promising data” on a long-awaited targeted treatment for immunoglobin A nephropathy (IgAN) were among the highlights of several late-breaking presentations at...
Fresenius Medical Care has made its own dialysis clinics available for the vaccination of its patients against COVID-19. Dialysis patients are an especially high-risk group due to the fact they are on average, over the age of 65, and often...
Acute kidney injury (AKI) treated with dialysis is reported to be a frequent complication in patients hospitalised with COVID-19. Research published online in the Clinical Journal of the American Society of Nephrology in late May reveals that machine learning...
Many individuals with kidney failure have been unable to self-isolate during the COVID-19 pandemic because they require dialysis treatments in clinics several times a week. New research that will appear in an upcoming issue of the Clinical Journal of...
Researchers from the Lawson Health Research Institute at London Health Sciences Centre (LHSC) in London, Canada have reported that a simple medical device reduced swelling after kidney transplantation, as well as shortening hospital stays and decreasing surgical site infections,...
 Andrew Holden (Auckland, New Zealand) presents the latest results from the IN.PACT™ AV Access trial (Medtronic), which indicate “outstanding” target-lesion primary patency rates of 52.2% through 24 months in dialysis patients with dysfunctional arteriovenous fistulas (AVFs), offering a “highly-significant advantage” over standard...
Following a successful proof-of-concept study, Gerard S Goh and Markus P Schlaich have embarked upon a first-in-human study to explore the safety and efficacy of combined renal and common hepatic artery denervation in patients with type 2 diabetes and...
The field of vascular access care for haemodialysis patients may look very different in just a few years’ time, with a host of new, innovative technologies currently being developed and tested to help tackle existing challenges relating to infection,...
Those living with kidney disease need better, more relevant patient education to best participate in the decision-making about their treatment, a new study published in the National Kidney Foundation (NKF)’s American Journal of Kidney Diseases (AJKD) shows. In a report...
In addition to demonstrating comparable performance in terms of long-term patency, durability and associated complications, early-cannulation arteriovenous (AV) grafts may hold some advantages when contrasted with standard expanded polytetrafluoroethylene (ePTFE) graft products. That is according to transplant and vascular...
The European Union (EU) Medical Devices Regulation (MDR) takes effect from today (26 May 2021). The Regulation revises quality and safety standards and the range of regulated devices and was first initiated in May 2017, with an initial three-year transition...
Procyrion has announced the treatment of the first patients in a pilot trial to evaluate the performance of its novel Aortix percutaneous mechanical circulatory support (pMCS) device in patients with cardiorenal syndrome (CRS). The company began its trial in...
 Ajay Kirtane (New York, USA) talks to Renal Interventions about the RADIANCE-HTN TRIO trial which compared renal denervation with a sham procedure to see whether or not renal denervation could lower blood pressure out to two months in patients...
Additional randomised controlled data regarding the effectiveness of drug-coated balloons (DCBs) in maintaining arteriovenous (AV) access offers new evidence, but it is freighted with uncertainty. However, specific modelling suggests fewer reinterventions could reinforce economic benefits when the IN.PACT AV...
Ultrasound-based endovascular renal denervation can successfully reduce systolic blood pressure in patients with medication-resistant hypertension, as demonstrated by the results of a late-breaking clinical trial presented at the American College of Cardiology’s 70th Annual Scientific Session (ACC.21, 15–17 May,...
Through its Renal Therapies Group, Fresenius Medical Care North America (FMCNA) has introduced the Kinexus Therapy Management Platform—a new connected health platform for home dialysis that supports the management of a patient's peritoneal dialysis therapy on the company’s Liberty...
Medtronic today announced new clinical data from the Global SYMPLICITY registry (GSR) indicating that renal denervation with the Medtronic Symplicity renal denervation system was associated with clinically significant and sustained blood pressure reductions in a real-world hypertensive patient population...
American healthcare firm and global renal care innovator Baxter International has announced US Food and Drug Administration (FDA) 510(k) clearance of its next-generation Artificial Kidney 98 (AK 98) dialysis machine, which is designed to be a portable and easy-to-use...
In a recent study, Victor Demaerel (University Hospitals Leuven, Leuven, Belgium) and colleagues found that tunnelled haemodialysis catheter (THC) survival in 352 patients was more than 70% after five years. This finding, they conclude, “supports use for permanent...
Despite currently being less commonly used than metal needles in haemodialysis access, particularly in Europe, plastic cannulas offer a “useful new tool in the box” for renal nurses, thanks to their ability to lessen blood extravasation and reduce the...
In its current form, postprocedural surveillance of arteriovenous grafts (AVGs) used to treat venous stenosis is “little more than supervised neglect”, and should be re-evaluated using the right patient cohorts and treatment strategies. That is according to a discussion...
Transit Scientific has announced CE mark clearance for its XO Score scoring sheath platform, allowing the technology to be used in the treatment of peripheral arterial disease (PAD) and end-stage renal disease (ESRD) within the European Union. XO Score is...
Discussions at this year’s Charing Cross (CX) 2021 Digital Edition (19–22 April, online) indicated that high-flow arteriovenous (AV) fistulas remain one of the more divisive topics in the field of vascular access. This was most apparent in the outcome...
Invizius has announced the closing of a Series A financing round worth £5.3 million. The Scottish biotechnology company will use this funding to complete a first-in-man safety study next year of its H-Guard Priming Solution, which is intended to...
Metavention, a Minneapolis-headquartered medical device company, has announced the initiation of the MODUS study to treat patients with both type 2 diabetes and hypertension using a minimally-invasive, catheter-based approach. The first procedures in this study were successfully completed at The...
A new wearable device designed to remotely monitor arteriovenous (AV) fistulae function in dialysis access patients uncovered promising data leading one set of researchers to conclude the technology offers hope for improved care and lower costs among a challenging...
iVascular has received CE mark approval for its balloon-expandable covered stent, iCover, a press release from the company states. Balloon-expandable covered stents are commonly used for treating arteriosclerotic lesions in renal and iliac arteries, and for the treatment of aneurysms...
Vascular Therapies recently announced results from its phase 3 clinical trial in which Sirogen showed encouraging arteriovenous fistula (AVF) outcomes in elderly end-stage renal disease (ESRD) patients. Sirogen is the company's proprietary sirolimus formulation for intraoperative local drug delivery to...
BD announced today that enrolment has begun and the first patients have been treated in the postmarket surveillance study, CONNECT-AV. CONNECT-AV is a prospective, single-arm, open-label study that will follow patients treated with the WavelinQ endovascular arteriovenous fistula (endoAVF) system...
A small, randomised trial conducted in a UK dialysis unit has found that ultrasound guidance can improve cannulation accuracy—and this improvement may be most profound in arteriovenous (AV) fistulas that are more difficult to cannulate. These findings, which were presented...
Medtronic recently announced the safety and effectiveness results through 24 months for the IN.PACT AV Access clinical study. The data, which were presented virtually as a Podium 1st at the Charing Cross (CX) 2021 Digital Edition (19–22 April, online)...
Massachusetts-based physician organisation InterWell Health has announced the closing of a Series B funding round worth US$46 million. The company claims this funding round will bring together more than 1,000 nephrologist investors representing 55 different nephrology practices and 31...
Consensus is split over the need for flow reduction in high-flow fistulas to avoid cardiac complications in dialysis patients, polling taken during the Charing Cross (CX) 2021 Digital Edition (19–22 April, online) has revealed. Attendees to the Vascular Access...
Clotted haemodialysis accesses can spontaneously recanalise following a failed thrombectomy and subsequent abandonment, a retrospective review of 3,137 mechanical thrombectomy procedures has found. The study was presented at the 2021 meeting of the Society of Interventional Radiology (SIR; 20–26...
American medical technology company BD (Becton, Dickinson and Company) has received 510(k) clearance from the US Food and Drug Administration (FDA) for its Pristine long-term haemodialysis catheter—a new haemodialysis catheter with a unique side hole-free symmetric Y-tip distal lumen...
A multicentre clinical trial to assess arteriovenous fistula (AVF)-first and arteriovenous graft (AVG)-first access strategies in older end-stage renal disease (ESRD) patients on haemodialysis has been deemed feasible following a two-year pilot study investigating the same topic. The findings of...
Shanghai-based renal denervation (RDN) company Brattea has announced the successful completion of a Series B+ funding round worth more than US$20 million led by healthcare private equity fund Kuanping Capital.  According to a press release from Brattea, this is the...
Cricket Health has announced a new kidney care programme specifically designed for late-stage chronic kidney disease (CKD) and end-stage renal disease (ESRD) patients enrolled in Medicare Advantage (MA) plans. The US company claims its programme—which has been launched to more...
Surmodics recently announced the successful first uses with patients for two devices within its Sublime radial access platform: the Sublime radial access guide sheath and Sublime radial access .014 RX percutaneous transluminal angioplasty (PTA) dilatation catheter. Constantino Pena, Andrew Niekamp,...
While there is large variability based on the site of insertion, patient characteristics and previous accesses, fluoroscopically-guided insertion of tunnelled central venous catheters (td-CVC) for dialysis can be considered a “low exposure” procedure, according to a report. The report, which...
“International practice differences exist in cannulation and dialysis provision with some approaches aiming for fistulas to suit the logistics of dialysis, rather than best long-term outcomes for the fistula and the patient” The CX 2021 Vascular Access Controversies Programme is designed to...
Fresenius Medical Care North America and DaVita Kidney Care have announced an expanded agreement to make multiple home dialysis technologies available for patients across the USA. Following this new agreement between the two American companies—which intends to encourage more people...
MedAlliance has announced completion of patient enrolment in the ISABELLA clinical trial with the Selution SLR 018 drug-eluting balloon (DEB) for the treatment of dysfunctional arteriovenous (AV) fistulas in end-stage renal failure patients undergoing haemodialysis. Selution SLR (sustained limus...
NOTE: This video is ONLY available to watch in selected countries and geographies Robert Lookstein (New York, USA; principal investigator) and Andrew Holden (Auckland, New Zealand; principal investigator) discuss the key six-month results and implications from the IN.PACT™ AV...
 A trio of vascular experts including Raphaël Coscas (Paris, France), Alexandros Mallios (Paris, France) and Kate Steiner (Stevenage, UK) discuss the key findings of the IN.PACT™ AV Access trial–which was recently published in the New England Journal of Medicine...
New data presented for the first time at LINC 2021 (The Leipzig Interventional Course; 25–29 January, online) support the use of drug-coated balloons (DCBs) as a treatment for dysfunctional arteriovenous fistulas (AVFs). The audience also heard the case for...
Humacyte has announced that the clinical results of five-year outcomes in patients receiving the human acellular vessels (HAV) for arteriovenous (AV) access in haemodialysis have been accepted for oral presentation at the Charing Cross (CX) Symposium (19–22 April, online)....
A tunneled catheter remains the most common access in patients initiating haemodialysis.1 This is most likely because the catheters are ready to use immediately after insertion, with no maturation time needed. As with any other dialysis access, hydraulic performance...
Panagiotis M Kitrou and Nicholas Inston discuss the impact of the COVID-19 pandemic on vascular access services. Despite the disruption caused, they are optimistic that the pandemic should be viewed as a catalyst for change. It is time to...
NOTE: This video is ONLY available to watch in selected countries and geographies Tobias Steinke (Düsseldorf, Germany), Matteo Tozzi (Varese, Italy) and Robert Shahverdyan (Hamburg, Germany) give their reactions to the publication in the New England Journal of Medicine...
The CX 2020 LIVE Vascular Access Consensus session sparked global interest, with chair Nick Inston (Birmingham, UK) and moderator Domenico Valenti (London, UK) taking questions from 17 countries, spanning South America to South East Asia. The session pinpointed the...
PatenSee has initiated a first-in-human clinical trial to assess its machine vision-based surveillance system, a press release from the company reveals. The trial, led by Benaya Rozen-zvi, director of the Institute for Nephrology and Hypertension at Rabin Medical Center...
Renal artery involvement (RAI) in endovascular aneurysm repair (EVAR) is “highly predictive of the need for postoperative and permanent dialysis,” Anastasia Plotkin (University of Southern California, Los Angeles, USA) and colleagues write in the Journal of Vascular Surgery (JVS)....
Medtronic has announced the launch of IN.PACT AV drug-coated balloon (DCB) in Japan. IN.PACT AV DCB is indicated for the treatment of obstructive lesions up to 100mm in length in the native arteriovenous (AV) dialysis fistulae in patients with...
Nicholas Inston (Birmingham, UK; moderator) is joined by Jose Ibeas (Barcelona, Spain), Panagiotis Kitrou (Patras, Greece) and Tobias Steinke (Düsseldorf, Germany), for a special Vascular News webinar called ‘WavelinQ™ 4F EndoAVF System – An attractive non-surgical AV fistula option for...
There is no evidence of a benefit from additional paclitaxel-coated balloon use compared to standard balloon angioplasty alone in the context of preserving arteriovenous (AV) fistula patency for haemodialysis, according to as-yet unpublished data from the multicentre, randomised controlled...
Merit Medical Systems recently announced the enrolment of the first patients in its Wrapsody arteriovenous (AV) access efficacy pivotal (WAVE) study of the Wrapsody endovascular stent graft, an investigational device being studied for the treatment of stenosis or occlusion within...
Nicholas (Nick) Inston calls for “more creative solutions” to vascular access challenges, commending interventional radiologists’ innovative reputation as instrumental to increasing the number of treatment approaches available to physicians. Outlining the complexities of end-stage vascular access in an ever-increasing...
Ureteral stents (hollow devices placed in the ureter - the tube between the kidney and bladder) can be used temporarily to relieve urinary obstruction in patients with kidney stones. Despite the use of antibiotics, ureteral stents often become encrusted...

Matteo Tozzi

Charmaine Lok

Alexandros Mallios