Fluidx Medical has announced completion of trial enrolment for its GPX embolic device. In this multicentre trial, GPX was used to treat a variety of primary and metastatic tumours, renal adenoma tumours, and in a range of other arterial and venous applications.
“We are pleased to announce the enrolment of the final patient in the trial and look forward to participating in future trials using this promising technology,” stated the trial’s principal investigator, Andrew Holden (Auckland City Hospital, Auckland, New Zealand). “In the trial, GPX showed significant potential to advance liquid embolics, penetrating very distally, providing profound embolisation, and demonstrating excellent radiopacity, which helped to avoid non-target embolisation and preserve healthy adjacent tissue.”
GPX has shown promising results for tumour embolisation and other uses where there is a desire for distal vessel bed penetration. Embolisation is a procedure in which arterial or venous blood supply to an organ, malformation, aneurysm, bleed, tumour, and/or other abnormal area of issue is blocked.
Interim results of the GPX study have been presented at recent annual congresses including the Global Embolization Symposium & Technologies (GEST), Society of Interventional Radiology (SIR), and Leipzig Interventional Course (LINC).
Holden concluded: “We have only touched on some of the applications. Further trials will provide opportunities to look at broader applications of this product. We believe it will be an exciting addition to the embolic portfolio for interventionalists.”
GPX is an innovative embolic designed for simple preparation and controllable material delivery. The device is packaged ready-to-use in a syringe, can be prepped tableside by the clinician in about 30 seconds, and may be delivered through standard microcatheters (no complex mixing systems or special delivery catheters are necessary). GPX technology is a low viscosity, aqueous-based solution in a syringe that solidifies into a durable embolus upon delivery without polymerisation or dimethyl-sulfoxide (DMSO) precipitation.