Tag: transplantation
Artificial kidney breakthrough as bioreactor survives in pig model without immune...
Scientists at the University of California San Francisco (UCSF) are working on a new approach to treating kidney failure that could one day free...
Pig kidney xenotransplantation performing “optimally” after 32 days in human body
Surgeons at New York University (NYU) Langone Health (New York, USA) have transplanted a genetically engineered pig kidney that continues to function well after...
Phase 1 study of kidney transplant rejection drug initiated
Tonix Pharmaceuticals has announced the initiation of a Phase 1 single ascending dose escalation study of TNX-1500 (Fc-modified humanized anti-CD40L monoclonal antibody or mAb),...
HLA-incompatible kidney transplant may raise colorectal cancer risk
New research led by Jennifer Motter (New York University Grossman School of Medicine, New York, USA) has investigated the link between human leukocyte antigen...
Sleep quality declines among female kidney transplant recipients
New research published in Nephrology Dialysis Transplantation has found that fatigue, concentration issues, and social disengagement are among the problems experienced by kidney transplant...
Mitochondrial transplantation found effective in reversing kidney damage
A new preclinical study, led by scientists at Wake Forest University School of Medicine (Winston-Salem, USA), shows that a new technology called mitochondrial transplantation holds...
Blood transfusion for anaemia associated with worse kidney graft outcomes
The “urgent development of transplant-specific anaemia guidelines” and a need for “rigorous patient blood management (PBM)” for those who receive kidney transplants—these are among...
First US living HIV-to-HIV kidney transplant donors achieve positive outcomes
Based on findings from a new study published in the journal The Lancet Regional Health – Americas, researchers at Johns Hopkins Medicine and three collaborating...
Imlifidase receives provisional approval in Australia for kidney transplant desensitisation
Hansa Biopharma has announced that the Australian Therapeutic Goods Administration (TGA) has provisionally approved Idefirix (imlifidase) as desensitisation treatment for highly sensitised patients prior...
Xenotransplantation company wins KidneyX award for genetically-engineered donor pig
Makana Therapeutics has announced that it has been awarded an Artificial Kidney Phase II Prize from KidneyX to continue development of its genetically engineered...
New urine test could explain kidney transplant rejections
The day when a urine test can inform a doctor precisely why a kidney transplant patient is experiencing organ rejection, and help to suggest...
Earlier dialysis, transplantation show little benefit for young kidney patients
Published in the Clinical Journal of the American Society of Nephrology (CJASN), a new report has examined the timing of initiation of kidney replacement...
Metabolic syndrome changes associated with kidney graft failure
A new study in Nephrology Dialysis Transplantation has examined the relationship between metabolic disorder (MetS) and adverse outcomes in recipients of kidney transplants. The...
Some US kidney waitlist candidates passed over for less urgent candidates
A new study by Columbia University Irving Medical Centre (CUIMC; New York, USA) researchers has found that some US centres routinely skip their highest-ranking...
Posoleucel safe and effective for BK infection in kidney transplant recipients,...
AlloVir, a late-clinical stage allogeneic T cell immunotherapy company, has announced the presentation of final results from a Phase 2 study of posoleucel, an...
New kidney graft function risk model promises more accurate prognosis
A team of researchers led by Shaifali Sandal (McGill University Health Centre, Montreal, Canada) has shared the results of a study evaluating a new...
Renal Interventions 7 – EU
Highlights
First-in-human study of a regenerative material for dialysis access demonstrates initial safety and mechanical durability.
Interventional nephrology's place in kidney care explored following...
Renal Interventions 7 – US
Highlights
First-in-human study of a regenerative material for dialysis access demonstrates initial safety and mechanical durability.
Interventional nephrology's place in kidney care explored following...
Xenotransplantation data presented on porcine donor kidneys
During the National Kidney Foundation's (NKF) Spring Clinical Meetings (11–15 April, Austin, USA), researchers from Massachusetts General Hospital (Boston, USA) will present new data...
Kidney Transplant Collaborative announces second phase of funding
The Kidney Transplant Collaborative (KTC) has received significant new funding that it says will “empower the organisation’s mission to reduce barriers in the transplant...
Talaris Therapeutics announces restructuring and clinical trial discontinuations
Talaris Therapeutics has announced that it has completed a review of its business and programme prospects. Based on this review, Talaris has decided to...
National Kidney Foundation honours Johns Hopkins’ Tanjala Purnell for transplantation research
Next month, Tanjala S Purnell (Johns Hopkins University, Baltimore, USA) will receive the National Kidney Foundation's (NKF) Excellence in Transplantation Award at the 2023...
“Urgently deliver” pre-emptive living donor kidney transplantation “as the default”
Living-donor kidney transplantation should be “treatment of choice” over deceased-donor transplantation, owing to it being the “most secure way to achieve pre-emptive kidney transplantation”....
Organ Utilisation Group recommends “standardised patient pathways” for transplantation
A report has been issued on methods for improving organ provision by the Organ Utilisation Group (OUG), a UK Department of Health-established body dedicated...
Most kidneys declined by patients for donor-related reasons later found viable
The “overwhelming majority” of previously-rejected deceased donor kidneys that have later been used for transplantation have been found viable by a new study published...
Genetically-modified pig patent promises expansion of kidney xenotransplantation
Makana Therapeutics, a global leader in the field of xenotransplantation, was granted an important European patent that will catalyse xenotransplantation efforts abroad, the company...
Michelle A. Josephson to become next president of the American Society...
The American Society of Nephrology (ASN) has announced that Michelle A. Josephson will become the society’s next president. Josephson, who succeeds Susan E. Quaggin,...
Study suggests infection concerns “should not affect” implementation of ABOi kidney...
Concerns regarding infectious complications should not affect the implementation of ABO-incompatible (ABOi) kidney transplant programmes, as per the findings from a nationwide, prospective cohort...
New guideline supports kidney exchange programmes and “integrated approach” in sensitised...
A new guideline on the management of highly sensitised kidney transplant patients—those who have high levels of human leukocyte antigens (HLAs) and are therefore more...
SGLT2 inhibitors demonstrate efficacy and safety in diabetic kidney transplant recipients
Sodium-glucose cotransporter-2 (SGLT2) inhibitors can be used safely to help preserve graft function in diabetic kidney transplant recipients, as per the findings from a...
Stanford paediatricians transplant kidneys without need for immunosuppressants
Physicians at Stanford Medicine (Stanford, USA) have developed a way to provide paediatric kidney transplants without immunosuppressant drugs. Their key innovation, according to a Stanford press...
Machine learning fails to outperform traditional models in predicting long-term allograft...
A study presented at this year’s American Transplant Congress (ATC; 4–8 June, Boston, USA) found that machine learning (ML) technologies did not outperform traditional...
Mayo Clinic study confirms living kidney donor surgery is low risk...
The risk of major complications for people who donate a kidney via laparoscopic surgery is minimal. That is the conclusion of a 20-year Mayo...
Select solid-organ transplant recipients may remain at high Omicron risk despite...
While a fourth vaccine dose does increase anti-spike immunoglobin-G (IgG) and neutralising capacity against many COVID-19 variants of concern (VOCs), some solid-organ transplant recipients...
X-Therma receives FDA Breakthrough Device designation for organ preservation and transport...
X-Therma has announced that the Center for Devices and Radiological Health (CDRH) of the US Food and Drug Administration (FDA) has granted its proprietary...
Canadian government invests CA$2 million into AI-based organ donation research
In recognition of the fact that “too many” people in Canada are on organ waitlists, with Canada also lagging behind other high-performing countries in...