Tag: kidney transplantation
Normothermic machine perfusion may improve renal function in deceased donor kidneys
Despite not reducing rates of delayed graft function in kidneys from donation after circulatory death (DCD) donors, the novel organ storage technique of normothermic...
Post-kidney transplant delirium associated with sevenfold greater risk of dementia
Transplant centres “should be aware” of the cognitive risks associated with post-kidney transplant delirium and should also implement available preventative interventions to reduce delirium...
Study suggests infection concerns “should not affect” implementation of ABOi kidney...
Concerns regarding infectious complications should not affect the implementation of ABO-incompatible (ABOi) kidney transplant programmes, as per the findings from a nationwide, prospective cohort...
New guideline supports kidney exchange programmes and “integrated approach” in sensitised...
A new guideline on the management of highly sensitised kidney transplant patients—those who have high levels of human leukocyte antigens (HLAs) and are therefore more...
SGLT2 inhibitors demonstrate efficacy and safety in diabetic kidney transplant recipients
Sodium-glucose cotransporter-2 (SGLT2) inhibitors can be used safely to help preserve graft function in diabetic kidney transplant recipients, as per the findings from a...
American Society of Nephrology leads renewed call for US congress to...
Members of the American Society of Nephrology (ASN) and 21 organisations representing the kidney community—patients and healthcare professionals alike—recently met with their corresponding members...
Cambridge researchers alter blood type of deceased donor kidneys with ‘molecular...
Researchers at the University of Cambridge (Cambridge, UK) have successfully altered the blood type of three deceased donor kidneys—a breakthrough that could have major...
Fistula ligation “should become a routine part of post-transplant care”
At this year’s Vascular Access for Hemodialysis Symposium (9–11 June, Charleston, USA), Alexander Toledo (University of North Carolina, Chapel Hill, USA) asserted the advantages...
AlloVir reports preliminary data on posoleucel for BK viraemia in kidney...
AlloVir has announced preliminary, blinded data from an ongoing Phase 2 study of posoleucel—an investigational, allogeneic, off-the-shelf, multi-virus-specific T cell (VST) therapy for the...
NICE recommends Idefirix in treatment of highly sensitised kidney transplant recipients
Hansa Biopharma has announced a recommendation by the National Institute for Health and Care Excellence (NICE) for its first-in-class treatment Idefirix (imlifidase) in the...
Select solid-organ transplant recipients may remain at high Omicron risk despite...
While a fourth vaccine dose does increase anti-spike immunoglobin-G (IgG) and neutralising capacity against many COVID-19 variants of concern (VOCs), some solid-organ transplant recipients...
First patient dosed in study evaluating TX200 cell therapy product for...
Sangamo Therapeutics has announced dosing of the first patient in the Phase 1/2 STEADFAST clinical study evaluating TX200—an investigational, wholly owned, autologous chimeric antigen...
Retransplantation may offer greater survival outcomes than dialysis following a failed...
As per a clinical study involving more than 2,300 adult patients, a second kidney transplant is likely to offer improved survival outcomes when compared...
Natera announces study results showing “excellent” positive predictive value of Prospera...
Natera has announced the results of a large clinical experience study confirming the "strong performance" of its Prospera donor-derived cell-free DNA (dd-cfDNA) test in...
Transplantation discrepancies contribute to racial disparities in childhood-onset kidney failure survival...
Transplantation discrepancies between Black and white patients have been found to contribute significantly to differing survival rates for childhood-onset kidney failure across the two...
Transplantation of gene-edited pig kidneys in decedent human model is “game-changing...
Peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual has been published in the American Journal...
DaVita expands efforts in kidney transplantation with MedSleuth acquisition
DaVita has announced the acquisition of transplant software company MedSleuth, which works with US transplant centres to improve experiences and outcomes for kidney and...
GIRFT report represents “call to action” and provides renewed focus for...
The Getting It Right First Time (GIRFT) national report on renal medicine represents a “call to action” for the UK renal community, and provides...
Standard vaccination regimens may not provide adequate protection against new SARS-CoV-2...
Kidney transplant recipients tend to mount impaired antibody responses against emerging SARS-CoV-2 variants after standard two-dose COVID-19 vaccination, according to a study published in the...
Hansa Biopharma enrols first patient in US pivotal trial of kidney...
Hansa Biopharma recently announced that the first patient has been enrolled in its CONFIDES trial—a US pivotal, open-label, randomised controlled study—at the Columbia University Medical Center...
Promising histological marker of kidney graft failure identified by new study
An observational study published in the Journal of the American Society of Nephrology (JASN) has identified a “promising” histological marker for determining kidney transplant...
OrganOx completes £6.4 million equity fundraise to boost utilisation of donated...
OrganOx, the producer of the 'metra' normothermic machine perfusion (NMP) product, has announced the completion of a £6.4 million equity fundraise. The fundraise was...
Natera validates kidney transplant rejection test in multicentre, prospective Trifecta study
Natera has announced initial results from the global, multicentre, prospective Trifecta study, which assessed its Prospera with quantification test for kidney transplant rejection and was led by Phil...
Transformative moment marks progress in xenotransplantation
The first investigational transplantation of a genetically engineered, non-human kidney to a human body was recently completed at NYU Langone Health, New York, USA—marking...
Fresenius Medical Care North America announces three key clinical leadership appointments
Fresenius Medical Care North America (FMCNA) has announced three key clinical leadership appointments to help drive priorities, including improving patient outcomes, adopting connected health technologies...
Bioartificial kidney device receives KidneyX award after progressing to preclinical model
An implantable bioartificial kidney device (iBAK)—which promises to free kidney disease patients from dialysis machines and transplant waiting lists—has taken another step towards becoming...
Natera launches Prospera with quantification to improve kidney graft rejection testing
Natera has announced the launch of Prospera with quantification, the only cell-free DNA (cfDNA) test for kidney rejection that provides three values—the quantity of...
ESOT 2021: Asian donor and Black recipient kidney grafts associated with...
Black transplant recipients and patients who received kidneys from Asian donors had a significantly higher risk of their kidney grafts failing within seven years,...
ESOT 2021: Kidney transplants plummeted by 40% during first wave of...
The number of solid organ transplants performed during the first wave of the COVID-19 pandemic in 2020 plunged by nearly a third (31%) compared...
Rubicon Founders launches Evergreen Nephrology with intent to “transform” kidney care
Rubicon Founders has announced the launch of Evergreen Nephrology—a company partnering with nephrologists to transform kidney care, according to a press release. Evergreen is...
Pilot study of third COVID-19 vaccine dose in kidney transplant recipients...
A pilot study has begun to assess the antibody response to a third dose of an authorised COVID-19 mRNA vaccine in kidney transplant recipients...
NKF publishes recommendations to move thousands of patients from dialysis to...
The National Kidney Foundation (NKF) has released a position paper, developed by 16 nephrology experts from 13 institutions, with recommendations designed to navigate future research...
Hansa Biopharma announces three-year graft survival of 84% after imlifidase treatment...
Hansa Biopharma has announced three-year follow-up data on graft survival rates in crossmatch positive patients who received imlifidase prior to kidney transplantation. As reported...
Higher kidney transplant referral rates found in non-profit dialysis facilities versus...
New research indicates that patients with kidney failure who receive care at for-profit dialysis facilities are less likely to be referred for kidney transplants...
Novel device reduces swelling and surgical site infection after kidney transplantation
Researchers from the Lawson Health Research Institute at London Health Sciences Centre (LHSC) in London, Canada have reported that a simple medical device reduced...